Protein Alignment NMUR2 and Nmur2

DIOPT Version :10

• Sequence 1: NP_064552.3
• Gene: NMUR2 / 56923
• HGNCID: 16454
• Length: 415
• Species: Homo sapiens
• Sequence 2: NP_694719.2
• Gene: Nmur2 / 216749
• MGIID: 2441765
• Length: 395
• Species: Mus musculus
• Alignment Length: 399
• Identity: 315/399 - (78%)
• Similarity: 349/399 - (87%)
• Gaps: 5/399 - (1%)

Human     4 MEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLVCL 68
            |.||:|||||:     |...|:|||||||||:||||:||...|||||||..|||||||||:||||
Mouse     1 MGKLENASWIH-----DSLMKYLNSTEEYLAYLCGPKRSDLSLPVSVVYALIFVVGVIGNLLVCL 60

Human    69 VILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCFAS 133
            ||.:||.:|||||||||||||||||||||||||||||:|.|||||||||||||||||||||||||
Mouse    61 VIARHQTLKTPTNYYLFSLAVSDLLVLLLGMPLEVYELWHNYPFLFGPVGCYFKTALFETVCFAS 125

Human   134 ILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLV 198
            |||:||||:||||||:|||||||:||||||||||.:||.|||:|||||||||||||..|||||.|
Mouse   126 ILSVTTVSIERYVAIVHPFRAKLESTRRRALRILSLVWSFSVVFSLPNTSIHGIKFQQFPNGSSV 190

Human   199 PGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCR 263
            ||||||||.||:|:||||||.||||||:||||:||||||||.||||:|:|||||:...||.||.|
Mouse   191 PGSATCTVTKPIWVYNFIIQATSFLFYILPMTLISVLYYLMGLRLKRDESLEADKVTVNIHRPSR 255

Human   264 KSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYN 328
            |||.||||||||||||||.|||:||||||||:||:|||||||||:||||||||||||||||||||
Mouse   256 KSVTKMLFVLVLVFAICWTPFHVDRLFFSFVDEWTESLAAVFNLIHVVSGVFFYLSSAVNPIIYN 320

Human   329 LLSRRFQAAFQNVISSFHKQWHSQHDPQLPPAQRNIFLTECHFVELTEDIGPQFPCQSSMHNSHL 393
            ||||||:|||:||:|...|..|.||.||.||||:.|||||||.||||||.|||||||||:||:.|
Mouse   321 LLSRRFRAAFRNVVSPSCKWCHPQHRPQGPPAQKVIFLTECHLVELTEDAGPQFPCQSSIHNTQL 385

Human   394 PAALSSEQM 402
            ......|::
Mouse   386 TTVPCVEEV 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NMUR2	NP_064552.3	7tmA_NMU-R2	46..338	CDD:320479	249/291 (86%)
		TM helix 1	46..73	CDD:320479	22/26 (85%)
		TM helix 2	80..106	CDD:320479	25/25 (100%)
		TM helix 3	119..149	CDD:320479	27/29 (93%)
		TM helix 4	161..183	CDD:320479	17/21 (81%)
		TM helix 5	213..242	CDD:320479	24/28 (86%)
		TM helix 6	261..291	CDD:320479	25/29 (86%)
		TM helix 7	306..331	CDD:320479	23/24 (96%)
		NmU-R2_C_term	331..397	CDD:466027	45/65 (69%)
Nmur2	NP_694719.2	7tm_GPCRs	38..330	CDD:475119	249/291 (86%)
		TM helix 1	40..64	CDD:320479	20/23 (87%)
		TM helix 2	73..95	CDD:320479	21/21 (100%)
		TM helix 3	112..134	CDD:320479	20/21 (95%)
		TM helix 4	157..173	CDD:320479	11/15 (73%)
		TM helix 5	206..229	CDD:320479	19/22 (86%)
		TM helix 6	259..281	CDD:320479	18/21 (86%)
		TM helix 7	298..323	CDD:320479	23/24 (96%)
		NmU-R2_C_term	323..389	CDD:466027	45/65 (69%)