Protein Alignment NMUR2 and nmur2

DIOPT Version :10

• Sequence 1: NP_064552.3
• Gene: NMUR2 / 56923
• HGNCID: 16454
• Length: 415
• Species: Homo sapiens
• Sequence 2: XP_002940961.1
• Gene: nmur2 / 100498226
• XenbaseID: XB-GENE-6046084
• Length: 397
• Species: Xenopus tropicalis
• Alignment Length: 401
• Identity: 262/401 - (65%)
• Similarity: 320/401 - (79%)
• Gaps: 11/401 - (2%)

Human     4 MEKLQNASWIYQQKL--EDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGVIGNVLV 66
            |:..||.::::...|  ::...::|||||||||:||||:||...||:::||..||::|||||.||
 Frog     1 MDDQQNITFMWPSHLPPDNSMMRYLNSTEEYLAYLCGPKRSRLSLPMTLVYATIFLIGVIGNTLV 65

Human    67 CLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCYFKTALFETVCF 131
            |||||:|..|:||||||||||||||||||||||||||||||.|||||||..||||||.|||||||
 Frog    66 CLVILKHHNMRTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWSNYPFLFGAWGCYFKTVLFETVCF 130

Human   132 ASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGS 196
            |||||:|||||||||||:|||:|||:|||.|||:||..:|.||:|||:||||.|||...||||||
 Frog   131 ASILSVTTVSVERYVAIIHPFQAKLKSTRSRALKILVTLWIFSILFSIPNTSTHGILLQYFPNGS 195

Human   197 LVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRP 261
            |:|.||||||::|:||||.||||||.|||:|||.||||||.||.::|:.|.|||||:.:.|:|||
 Frog   196 LIPDSATCTVVQPLWIYNCIIQVTSLLFYILPMGVISVLYCLMGIKLRGDHSLEADKMSVNVQRP 260

Human   262 CRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPII 326
            .|||:.|||||||:||.|||||||:||||||||.:|:|.||..|||.||||||||||||||||:|
 Frog   261 SRKSITKMLFVLVMVFGICWAPFHVDRLFFSFVLDWTEPLANAFNLTHVVSGVFFYLSSAVNPLI 325

Human   327 YNLLSRRFQAAFQNVISSFHKQWHSQHDPQLP-----PAQRNIFLTECHFVELTEDIGPQFPCQS 386
            ||||||||::|||||:..|.|..    .|::|     |.:..:.||..:.::..|:..|.||.::
 Frog   326 YNLLSRRFRSAFQNVLPPFFKSL----KPKIPVQSLAPPKSTLILTVRNRMDSGEEGSPSFPHRT 386

Human   387 SMHNSHLPAAL 397
            |:.:|||...|
 Frog   387 SVCSSHLSTVL 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NMUR2	NP_064552.3	7tmA_NMU-R2	46..338	CDD:320479	222/291 (76%)
		TM helix 1	46..73	CDD:320479	18/26 (69%)
		TM helix 2	80..106	CDD:320479	25/25 (100%)
		TM helix 3	119..149	CDD:320479	27/29 (93%)
		TM helix 4	161..183	CDD:320479	13/21 (62%)
		TM helix 5	213..242	CDD:320479	22/28 (79%)
		TM helix 6	261..291	CDD:320479	23/29 (79%)
		TM helix 7	306..331	CDD:320479	22/24 (92%)
		NmU-R2_C_term	331..397	CDD:466027	24/70 (34%)
nmur2	XP_002940961.1	7tmA_NMU-R2	45..337	CDD:320479	222/291 (76%)
		TM helix 1	45..72	CDD:320479	18/26 (69%)
		TM helix 2	79..105	CDD:320479	25/25 (100%)
		TM helix 3	118..148	CDD:320479	27/29 (93%)
		TM helix 4	160..182	CDD:320479	13/21 (62%)
		TM helix 5	212..241	CDD:320479	22/28 (79%)
		TM helix 6	260..290	CDD:320479	23/29 (79%)
		TM helix 7	305..330	CDD:320479	22/24 (92%)
		NmU-R2_C_term	330..397	CDD:466027	24/70 (34%)