Protein Alignment PSMB4 and Prosbeta7

DIOPT Version :9

• Sequence 1: NP_002787.2
• Gene: PSMB4 / 5692
• HGNCID: 9541
• Length: 264
• Species: Homo sapiens
• Sequence 2: NP_649529.1
• Gene: Prosbeta7 / 40639
• FlyBaseID: FBgn0250746
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 103/258 - (39%)
• Similarity: 157/258 - (60%)
• Gaps: 6/258 - (2%)

Human    11 LWAGGPAPGQFYRIP--STPDSFMDPASALYRGP--ITRTQNPMVTGTSVLGVKFEGGVVIAADM 71
            :|..|||||:||...  .||...: |......||  ...:.....|||||||::::.||::|||.
  Fly    12 MWQNGPAPGEFYNFTGGQTPVQQL-PRELTTMGPYGTKHSTASSTTGTSVLGIRYDSGVMLAADT 75

Human    72 LGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSW 136
            |.||||:||::||.|:.:||.:.:||.|||:||.|.:|:.:.|.:|:::...|.....|:::.||
  Fly    76 LVSYGSMARYQNIERVFKVNKNILLGGSGDFADIQSIKRNIDQKMIEDQCCDDNIEMKPKSLASW 140

Human   137 LTRAMYSRRSKMNPLWNTMVIGGY-ADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLE 200
            :||.:|:|||:||||:..:|:||. .:|..:|..||:.|.:||...:|||:..:||.||:||...
  Fly   141 MTRVLYNRRSRMNPLYIDVVVGGVDNEGTPYLANVDLRGRSYEDYVVATGFARHLAVPLVREKKP 205

Human   201 KQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMISGF 263
            |....:..||.:|:..||.||||||.|:.:::.:...:..|..:|||.....||..|..|.|:
  Fly   206 KDRDFTAVEASELIRTCMEVLYYRDTRNISQYTVGVCSVNGCGVEGPFQVNENWTFAETIKGY 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PSMB4	NP_002787.2	proteasome_beta_type_4	52..247	CDD:239729	83/195 (43%)
Prosbeta7	NP_649529.1	proteasome_beta_type_4	60..252	CDD:239729	79/191 (41%)
		PRE1	60..232	CDD:223711	76/171 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155327
Domainoid	1	1.000	173	1.000	Domainoid score	I3714
eggNOG	1	0.900	-	-		E1_KOG0185
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2090
Inparanoid	1	1.050	207	1.000	Inparanoid score	I3707
Isobase	1	0.950	-	0	Normalized mean entropy	S1013
OMA	1	1.010	-	-		QHG53720
OrthoDB	1	1.010	-	-		D1228942at2759
OrthoFinder	1	1.000	-	-		FOG0004376
OrthoInspector	1	1.000	-	-		oto90521
orthoMCL	1	0.900	-	-		OOG6_101718
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1012
SonicParanoid	1	1.000	-	-		X3101
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750