DRSC/TRiP Functional Genomics Resources

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Protein Alignment UBQLN4 and ubqln4

DIOPT Version :10

Sequence 1:NP_064516.2 Gene:UBQLN4 / 56893 HGNCID:1237 Length:601 Species:Homo sapiens
Sequence 2:NP_998521.2 Gene:ubqln4 / 334337 ZFINID:ZDB-GENE-030131-6269 Length:599 Species:Danio rerio


Alignment Length:623 Identity:430/623 - (69%)
Similarity:488/623 - (78%) Gaps:46/623 - (7%)


- Green bases have known domain annotations that are detailed below.


Human     1 MAEPSG-------------AETRPPIRVTVKTPKDKEEIVICDRASVKEFKEEISRRFKAQQDQL 52
            |||.||             |.:...|:||||||||||||.|.:.|||.:||||||:||||:||||
Zfish     1 MAENSGTDPAVETNTEENAAASATIIKVTVKTPKDKEEIAIAEDASVAQFKEEISKRFKAKQDQL 65

Human    53 VLIFAGKILKDGDTLNQHGIKDGLTVHLVIKTPQKAQDPAAATASSPSTPDPASAPSTTPASPAT 117
            |||||||||||||||.||||||||||||||||.||.....::..|:.|.|.|:.      .||:.
Zfish    66 VLIFAGKILKDGDTLGQHGIKDGLTVHLVIKTAQKTSGAGSSQTSASSGPGPSQ------GSPSG 124

Human   118 PAQPSTSGSASSDAGSGSRRSSGGGPSPGAGEGSPSATASILSGFGGILGLGSLGLGSANFMELQ 182
            ...||.:|:..:..||        ||||     :||..|:||:|||.:.||.:||:|||||||||
Zfish   125 TDTPSPAGNLGTPQGS--------GPSP-----TPSQPANILAGFGDLSGLSNLGMGSANFMELQ 176

Human   183 QQMQRQLMSNPEMLSQIMENPLVQDMMSNPDLMRHMIMANPQMQQLMERNPEISHMLNNPELMRQ 247
            ||||||||||||||||||||||||.|||||||||.||||||||||||||||||||||||||||||
Zfish   177 QQMQRQLMSNPEMLSQIMENPLVQSMMSNPDLMRQMIMANPQMQQLMERNPEISHMLNNPELMRQ 241

Human   248 TMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSSLAGN 312
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|.||
Zfish   242 TMELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMFSAAREQFGNNPFSALGGN 306

Human   313 SDSSSSQPLRTENREPLPNPWSPSPPTSQAPGSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGM 377
            .::..:||.||||||||||||.|...|:....||...|..|.||...|:||||.||::::||:||
Zfish   307 GENPGTQPSRTENREPLPNPWGPPDGTASTTSSGTPTTTSSTTSSTTPSVSNPLGISSSNLGNGM 371

Human   378 FNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGNPQLQEQLRL 442
            ||||.||:|:||||||||||||:|||||||:|||:||||||.|:|:::|.||||||||||||:|.
Zfish   372 FNSPGMQSLMQQISENPQLMQNMISAPYMRTMMQSLAQNPDVASQVLMNNPLFAGNPQLQEQMRQ 436

Human   443 QLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLG--------SFGISRTP 499
            |||||||||||||:||::||||||:||:|||:||||||||||||:|.||        ..|:...|
Zfish   437 QLPVFLQQMQNPEALSVMTNPRAMRALMQIQEGLQTLQTEAPGLMPGLGPGGMPGGIPVGMPGAP 501

Human   500 APSAGSNAGSTPEAPTSSPATPATSSPT-GASSAQQQLMQQMIQLLAGSGNSQVQTPEVRFQQQL 563
            .|   :....|||.|..| ...:|.:|| |||.|||||||||:|:.|| |::..|||||||||||
Zfish   502 LP---TGVTVTPENPPPS-GQGSTPTPTAGASPAQQQLMQQMLQMFAG-GSASTQTPEVRFQQQL 561

Human   564 EQLNSMGFINREANLQALIATGGDINAAIERLLGSQLS 601
            |||::|||||||||||||||||||||||||||||||.|
Zfish   562 EQLSAMGFINREANLQALIATGGDINAAIERLLGSQPS 599

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UBQLN4NP_064516.2 Ubl_PLICs 11..83 CDD:340506 59/71 (83%)
rad23 13..>291 CDD:273167 205/277 (74%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 87..155 18/67 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 301..366 36/64 (56%)
STI1 393..>424 CDD:128966 25/30 (83%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 490..533 16/51 (31%)
UBA_PLICs 558..597 CDD:270582 36/38 (95%)
ubqln4NP_998521.2 Ubl_PLICs 25..96 CDD:340506 59/70 (84%)
rad23 26..311 CDD:273167 226/303 (75%)
UBA_PLICs 556..595 CDD:270582 36/38 (95%)

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