DRSC/TRiP Functional Genomics Resources

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Protein Alignment PSMB1 and Prosalpha1

DIOPT Version :9

Sequence 1:NP_002784.1 Gene:PSMB1 / 5689 HGNCID:9537 Length:241 Species:Homo sapiens
Sequence 2:NP_524837.2 Gene:Prosalpha1 / 45780 FlyBaseID:FBgn0263121 Length:244 Species:Drosophila melanogaster


Alignment Length:244 Identity:50/244 - (20%)
Similarity:95/244 - (38%) Gaps:54/244 - (22%)


- Green bases have known domain annotations that are detailed below.


Human    12 GRDLGMEPHRAAGPLQLRFSP--------YVF-----NGGTILAIAGEDFAIVASDTRLSEGFSI 63
            |...|.:.|...      |||        |.|     ...|.:|:...|.|:||:..:::|. :|
  Fly     4 GSSAGFDRHITI------FSPEGRLYQVEYAFKAIAQENITTVALKSGDCAVVATQKKVTEK-NI 61

Human    64 HTRDSPKCYKLTDKTVIGC--SGFHGDCLTLTKIIEARLKM--YKHSNNKAMTTGAIAAMLSTI- 123
            ........:::|..  |||  :|...|  :.:::.:||.:.  :::.....|....:...::.| 
  Fly    62 VPETVTHLFRITKD--IGCAMTGRIAD--SRSQVQKARYEAANFRYKYGYEMPVDVLCRRIADIN 122

Human   124 -LYSR--RFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKN 185
             :|::  ...|.....::...|.|...:||..||.|.:  ..|||             ..||.|.
  Fly   123 QVYTQNAEMRPLGCSMVLIAYDNEIGPSVYKTDPAGYF--SGFKA-------------CSVGAKT 172

Human   186 MQNVEHVP------LSLDRAMRLVKDVFISAAERDVYTGDALRICIVTK 228
            ::...::.      ||.::|::|......|....| :..:.:.|.:|:|
  Fly   173 LEANSYLEKKYKPNLSEEKAIQLAISCLSSVLAID-FKPNGIEIGVVSK 220

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PSMB1NP_002784.1 proteasome_beta_type_1 30..241 CDD:239726 47/226 (21%)
Prosalpha1NP_524837.2 PRE1 7..243 CDD:223711 49/241 (20%)
proteasome_alpha_type_6 8..218 CDD:239723 47/236 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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