DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PSMB1 and Prosalpha3T

DIOPT Version :9

Sequence 1:NP_002784.1 Gene:PSMB1 / 5689 HGNCID:9537 Length:241 Species:Homo sapiens
Sequence 2:NP_651843.1 Gene:Prosalpha3T / 43679 FlyBaseID:FBgn0261395 Length:251 Species:Drosophila melanogaster


Alignment Length:259 Identity:54/259 - (20%)
Similarity:91/259 - (35%) Gaps:74/259 - (28%)


- Green bases have known domain annotations that are detailed below.


Human     3 SSTAMYSAPGR----DLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSI 63
            |.|.::|..||    :..||   ||.           ..||.:.:..::..::|::..:.     
  Fly     7 SRTTIFSPEGRLYQVEYAME---AAS-----------QSGTCVGLLAKNGVLLATERSVD----- 52

Human    64 HTRDSPKCYKLTDKTV-----------IGC--SGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGA 115
                     ||.|.::           |.|  :|...|...|...:....:.|:.:..:.:....
  Fly    53 ---------KLMDTSIPVPRISWLNENIACCATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCEQ 108

Human   116 IAAMLSTILYSRRFF----PYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKA------GGSAS 170
            :...|..|..:...:    |:.|..:..|.|......:|..||.|:|  ..:||      .|:|.
  Fly   109 LVTNLCDIKQAYTQYGGKRPFGVSFLYMGWDCRFGFQLYQSDPSGNY--SGWKATCIGRKSGAAM 171

Human   171 AMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFIS----AAERDVYTGDALRICIVTKEG 230
            .|||         |.:.:..:|..|::.|    |||.|.    ...||..|.:.|.|..|.:.|
  Fly   172 EMLQ---------KELFSKGYVSPSVEEA----KDVAIKVMGMTLGRDSLTPEKLEIAFVQRYG 222

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PSMB1NP_002784.1 proteasome_beta_type_1 30..241 CDD:239726 45/228 (20%)
Prosalpha3TNP_651843.1 PTZ00246 1..241 CDD:173491 54/259 (21%)
Ntn_hydrolase 3..218 CDD:294319 52/253 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.