Protein Alignment PSMB1 and Prosalpha3T

DIOPT Version :10

• Sequence 1: NP_002784.1
• Gene: PSMB1 / 5689
• HGNCID: 9537
• Length: 241
• Species: Homo sapiens
• Sequence 2: NP_651843.1
• Gene: Prosalpha3T / 43679
• FlyBaseID: FBgn0261395
• Length: 251
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 54/259 - (20%)
• Similarity: 91/259 - (35%)
• Gaps: 74/259 - (28%)

Human     3 SSTAMYSAPGR----DLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSI 63
            |.|.::|..||    :..||   ||.           ..||.:.:..::..::|::..:.
  Fly     7 SRTTIFSPEGRLYQVEYAME---AAS-----------QSGTCVGLLAKNGVLLATERSVD----- 52

Human    64 HTRDSPKCYKLTDKTV-----------IGC--SGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGA 115
                     ||.|.::           |.|  :|...|...|...:....:.|:.:..:.:....
  Fly    53 ---------KLMDTSIPVPRISWLNENIACCATGNTADGNVLVNQLRMIAQQYQFNFGEMIPCEQ 108

Human   116 IAAMLSTILYSRRFF----PYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKA------GGSAS 170
            :...|..|..:...:    |:.|..:..|.|......:|..||.|:|  ..:||      .|:|.
  Fly   109 LVTNLCDIKQAYTQYGGKRPFGVSFLYMGWDCRFGFQLYQSDPSGNY--SGWKATCIGRKSGAAM 171

Human   171 AMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFIS----AAERDVYTGDALRICIVTKEG 230
            .|||         |.:.:..:|..|::.|    |||.|.    ...||..|.:.|.|..|.:.|
  Fly   172 EMLQ---------KELFSKGYVSPSVEEA----KDVAIKVMGMTLGRDSLTPEKLEIAFVQRYG 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PSMB1	NP_002784.1	proteasome_beta_type_1	30..241	CDD:239726	45/228 (20%)
Prosalpha3T	NP_651843.1	Ntn_hydrolase	3..218	CDD:469781	52/253 (21%)