DRSC/TRiP Functional Genomics Resources

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Protein Alignment PSMB1 and Prosalpha4T2

DIOPT Version :9

Sequence 1:NP_002784.1 Gene:PSMB1 / 5689 HGNCID:9537 Length:241 Species:Homo sapiens
Sequence 2:NP_001286844.1 Gene:Prosalpha4T2 / 37910 FlyBaseID:FBgn0017556 Length:252 Species:Drosophila melanogaster


Alignment Length:244 Identity:54/244 - (22%)
Similarity:86/244 - (35%) Gaps:48/244 - (19%)


- Green bases have known domain annotations that are detailed below.


Human     4 STAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDS 68
            :..:||..|..|.:|..:.|          |..|.|::.:...: |||....:.|.|.....|..
  Fly     8 AVTIYSPDGHLLQVEYAQEA----------VRRGSTVMGLRTNN-AIVIGVEKRSVGDLQEERMV 61

Human    69 PKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNN--KAMT----TGAIAAMLSTILYSR 127
            .|...|.|..|:..||...|...|  :..|:::...|..|  |..|    |..||.:......|.
  Fly    62 RKICMLDDHVVMTFSGLTADARIL--VSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSN 124

Human   128 RFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDN------------- 179
            ...|:.:..::||.||:|...::..||.|.:........|.:|   ||:.|.             
  Fly   125 GRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSS---QPVRDYMEKHADEILTIAD 186

Human   180 -------------QVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDV 215
                         .|...|...:|...|...:.:|::....::..||.|
  Fly   187 EAAAIKHIVRTLVSVSSLNHTQMEVAVLKYRQPLRMIDHQVLADLERTV 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PSMB1NP_002784.1 proteasome_beta_type_1 30..241 CDD:239726 48/218 (22%)
Prosalpha4T2NP_001286844.1 arc_protsome_A 5..215 CDD:163366 49/222 (22%)
Ntn_hydrolase 5..214 CDD:294319 49/221 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0638
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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