Protein Alignment CDC42SE1 and Spec2

DIOPT Version :10

• Sequence 1: NP_064624.1
• Gene: CDC42SE1 / 56882
• HGNCID: 17719
• Length: 79
• Species: Homo sapiens
• Sequence 2: NP_730968.1
• Gene: Spec2 / 40685
• FlyBaseID: FBgn0044823
• Length: 85
• Species: Drosophila melanogaster
• Alignment Length: 71
• Identity: 30/71 - (42%)
• Similarity: 39/71 - (54%)
• Gaps: 10/71 - (14%)

Human     3 EFWHK-LGCCVVEKPQPKKK---RRRIDRTMIGEPMNFVHLTHIGSG--EMGAGDGLAMTGAVQE 61
            |.|.: ..||..::..|.::   |.||||:|||.|.||||..||||.  |:.|.    ...|:..
  Fly     6 EIWLQWFSCCFQQQRSPSRRPHQRLRIDRSMIGNPTNFVHTGHIGSADVELSAN----RLNAIST 66

Human    62 QMRSKG 67
            ||:|||
  Fly    67 QMQSKG 72

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDC42SE1	NP_064624.1	Mediates phosphoinositide-binding	19..24		1/7 (14%)
		CRIB	29..67	CDD:412170	18/39 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..79		7/20 (35%)
Spec2	NP_730968.1	CRIB	35..75	CDD:238077	20/42 (48%)