DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PSMA5 and Prosbeta2R1

DIOPT Version :9

Sequence 1:	NP_002781.2	Gene:	PSMA5 / 5686	HGNCID:	9534	Length:	241	Species:	Homo sapiens
Sequence 2:	NP_572267.1	Gene:	Prosbeta2R1 / 31511	FlyBaseID:	FBgn0029812	Length:	307	Species:	Drosophila melanogaster

Alignment Length:	202	Identity:	50/202 - (24%)
Similarity:	87/202 - (43%)	Gaps:	28/202 - (13%)

- Green bases have known domain annotations that are detailed below.

Human    29 EAIKLGSTAIGIQTSEGVCLAVEKRIT-SPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLIDKA 92
            :|||.|::.:||...:||.|..:.|.| .|::...:..||..:..||.|..:|..||.:.:....
  Fly    43 KAIKTGTSIVGIIYKDGVILGADTRATEGPIVSDKNCSKIHHLQDHIYCCGAGTAADTEMITLTT 107

Human    93 RVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMD 157
            ..|...|.......:.|...:..:.....::          ....|.||:.||||..||||:.:.
  Fly   108 SAELDLHRLNTERRVPVVCASMMLRRTLFRY----------QGHIGAALVMGGVDTTGPQLYCIY 162

Human   158 PSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEEKLNA---------T 213
            |.|:..:....|:||.:..|.|.|:..:...:.|::.        ||::.|.::|         :
  Fly   163 PCGSNDKIPYAAMGSGTLAAMSVLEHGWKPDLDLEQG--------KQLVREAISAGVFNDLGSGS 219

Human   214 NIELATV 220
            ||:|..:
  Fly   220 NIDLCVI 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PSMA5	NP_002781.2	proteasome_alpha_type_5	8..220	CDD:239722	50/200 (25%)
Prosbeta2R1	NP_572267.1	20S_bact_beta	48..241	CDD:163402	47/197 (24%)
		proteasome_beta_type_7	49..236	CDD:239732	46/196 (23%)
		Pr_beta_C	241..274	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810