DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PSG11 and ceacam1

DIOPT Version :9

Sequence 1:	NP_002776.3	Gene:	PSG11 / 5680	HGNCID:	9516	Length:	335	Species:	Homo sapiens
Sequence 2:	NP_001107266.1	Gene:	ceacam1 / 114465	ZFINID:	ZDB-GENE-010724-14	Length:	1025	Species:	Danio rerio

Alignment Length:	317	Identity:	94/317 - (29%)
Similarity:	151/317 - (47%)	Gaps:	56/317 - (17%)

- Green bases have known domain annotations that are detailed below.

Human    31 PTTAQVMIEAQPPKVSEGKDVLLLVH-NLPQNL--------TGYIWYKGQIRDLYHYITSYVVDG 86
            |...||.:......|:.|.:|.|.|: ::|..:        |.::||.|.|.
Zfish    15 PGLCQVNVVPSNNPVAVGSNVTLDVNSSMPITVGLWLFGPSTLFMWYMGDII------------- 66

Human    87 QIIIYGPAYSGRETVYSNAS---LLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPK 148
                  |..|.:..||.|:|   |.:..||.|.:|.|.|.:.|.......:|        ||..:
Zfish    67 ------PGNSLQPGVYFNSSTYQLTLSAVTLESSGVYVLDVYKPNRIRSEIT--------LEVQE 117

Human   149 P------SISSSNLNPREAMETVILTCNPETPDASYLW--WMNGQS-LPMTHRMQLSETNRTLFL 204
            |      :::::||  .|..:||..||:..|   |.:|  |:||.| :....|:||..:.:||.:
Zfish   118 PVGNVNTTVNTTNL--VEVNDTVYFTCSVTT---SPVWFSWLNGNSAVKDGGRVQLQNSGQTLII 177

Human   205 FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI--FPSVTSYYSGENLDLSCFANSNP 267
            .|||:|..||::|.:.|:.|:.:|..:.||:.:||....:  .|..|.|.||.|..|||.|:|.|
Zfish   178 NGVTRYDEGPFKCVVVNNISSQQSVEMKLNISYGPGNLTLTAMPEKTVYISGSNFSLSCSADSKP 242

Human   268 PAQYSWTINGK-FQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIAP 323
            .|.::|.:||. ..::|......:.|...:|:|.|.|:|:||...::.:.|||::.|
Zfish   243 TATFNWMLNGNLLNVNGPVYVFTKATQNQSGVYTCGAQNAATLRYAAVTKTIRIVDP 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PSG11	NP_002776.3	Ig_CEACAM_D1	36..138	CDD:143251	27/113 (24%)
		IG_like	45..>121	CDD:214653	22/87 (25%)
		Cell attachment site. /evidence=ECO:0000255	127..129		0/1 (0%)
		Ig	148..236	CDD:299845	32/96 (33%)
		IG_like	163..223	CDD:214653	24/62 (39%)
		Ig_2	242..320	CDD:290606	27/80 (34%)
		IG_like	246..318	CDD:214653	25/72 (35%)
ceacam1	NP_001107266.1	Ig	32..115	CDD:299845	26/109 (24%)
		Ig	133..208	CDD:299845	28/77 (36%)
		IG_like	221..291	CDD:214653	25/69 (36%)
		Ig_2	221..284	CDD:290606	23/62 (37%)
		Ig	298..387	CDD:299845	1/2 (50%)
		Ig_2	400..469	CDD:290606
		IG	400..456	CDD:214652
		Ig	480..564	CDD:299845
		IG_like	494..559	CDD:214653
		IG_like	578..648	CDD:214653
		Ig_2	579..648	CDD:290606
		Ig_CEACAM_D4	650..741	CDD:143217
		IG_like	653..740	CDD:214653
		Ig_2	752..825	CDD:290606
		IG_like	755..825	CDD:214653
		Ig	827..917	CDD:299845
		IG_like	836..917	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I34796
eggNOG	1	0.900	-	-		E1_29WEF
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312709at7742
OrthoFinder	1	1.000	-	-		FOG0000658
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44337
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.920