Protein Alignment pak6b and Pak

DIOPT Version :9

• Sequence 1: NP_001155959.1
• Gene: pak6b / 567874
• ZFINID: ZDB-GENE-041014-121
• Length: 607
• Species: Danio rerio
• Sequence 2: NP_001138013.2
• Gene: Pak / 44039
• FlyBaseID: FBgn0267698
• Length: 840
• Species: Drosophila melanogaster
• Alignment Length: 801
• Identity: 238/801 - (29%)
• Similarity: 344/801 - (42%)
• Gaps: 224/801 - (27%)

Zfish     5 RKKK--KRKLE------------ISTPKNFQHRVHTSFDPVQGCFIGLPPQWQSLI--------E 47
            ||||  |.|::            ||.|.||:|.||..||.|.|.|.|:|..|..|:        |
  Fly    60 RKKKTLKSKIKGSKPSHTDSKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQE 124

Zfish    48 TLKRPKPVVDPSSF--TQVQVRPQKSIVRGSFIGHEDYISAAIAQMSRLSVTS------------ 98
            ..|.|:.|:|...:  ...:.||....:..:...|..      :.:||:|.:|
  Fly   125 QKKNPQAVLDVLKWFDNTTKQRPSSKYMTNAITTHSG------SSLSRVSSSSPSSTPTDSELHG 183

Zfish    99 SNS------LRRRSPSVRKRAQSLGRLGEL-----AEAETYEYEELNNTNHRNSSDLHRGSRPI- 151
            |||      ::..|.::...|.::...|::     .:.:.:..::.....|:|.:..|.|....
  Fly   184 SNSGGNLIGVQLGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSH 248

Zfish   152 ---------------------------QSPQTESRQSPARARSVHEATMFT--------GLMPRD 181
                                       |.||.:....|..:|.....:::|        .::|..
  Fly   249 SYNFVGHTVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPAIIPMP 313

Zfish   182 I--------------------------LLHRAGCEGTDNAGNKPNQRPVSCLYSQSDGAKLNSDQ 220
            :                          ::|.......|.  ||.|..|.|...:::..
  Fly   314 VAPATTPATPLQNHRTPGGISAPAASPMMHNNATTTLDK--NKNNATPTSPTTTKTTA------- 369

Zfish   221 LKMETQRRPQSTYDFKVNSPNL-------PAASKPNG------------------TSSPKPGHG- 259
               ||:....::......:|:.       ||.:.|.|                  ||:....|.
  Fly   370 ---ETEGTDATSTLLSATNPSCSTTPTTDPAPAAPRGSLVETATAHATTAAATVATSTTTNHHSS 431

Zfish   260 ---------------------IISMQTPRRSSTDNTLKLSTIPADVP-PAQDSPSEPRQAPSGAS 302
                                 .|...||..||.::|:   :.|..|| |...:|:.|  .|:...
  Fly   432 ASSFSSFPSFHDDDGTHHALPTIHCPTPTSSSRNSTV---SFPVAVPLPPIVTPASP--TPASIE 491

Zfish   303 SPGLTEPSVTHTQF-----------------------------RAA---------------LQMV 323
            ||.|..|..|..|.                             |||               |:.:
  Fly   492 SPDLYTPEPTVAQVSAGGPSSQVAGNQIAVPQAAVAPAATPNTRAANAKKKKMSDEEILEKLRTI 556

Zfish   324 VDPGDPRSYLENFIKIGEGSTGVVCIAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYRHQ 388
            |..|||........|||:|::|.|..|.|..:|.:||:|.|:|.:|.::||:.||:::||:.:|.
  Fly   557 VSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHP 621

Zfish   389 NVVEMYKSALVGEELWVIMEYLQGGALTNIVSETRLTEEQIATVCESVLQALCYLHSQGVIHRDI 453
            |||....|.||.|||||:||||.||:||::|:||.:.|.|||.||..|||||.:||:..||||||
  Fly   622 NVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDI 686

Zfish   454 KSDSILLTLDGRVKLSDFGFCAQISKDVPKRRSLVGTPYWMAPEVVSKTPYGTEVDIWSLGIMVV 518
            |||:|||.|||.|||:|||||||||.:..||.::||||||||||||::..||.:||:||||||.:
  Fly   687 KSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAI 751

Zfish   519 EMVDGEPPYFSETPISAMKRLRDEPPPTARNASKISPVLRDFLDSMLTREPQQRSSASDLLQHPF 583
            |||:|||||.:|.|:.|:..:.....|..:...|:|...:||||..|..|..:|:||.|||:|||
  Fly   752 EMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPF 816

Zfish   584 LLQCSSPRCLIPLVEQTRRRT 604
            |........|.||:...:..|
  Fly   817 LKLARPLASLTPLIMAAKEAT 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pak6b	NP_001155959.1	PBD	13..65	CDD:279166	22/73 (30%)
		STKc_PAK6	311..607	CDD:270821	152/338 (45%)
		S_TKc	338..584	CDD:214567	136/245 (56%)
Pak	NP_001138013.2	PBD	83..137	CDD:279166	22/53 (42%)
		STKc_PAK_I	558..818	CDD:270814	140/259 (54%)
		S_TKc	566..817	CDD:214567	136/250 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757766at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920