DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aebp1b and DIP-epsilon

DIOPT Version :9

Sequence 1:	XP_696022.6	Gene:	aebp1b / 567630	ZFINID:	ZDB-GENE-030131-8546	Length:	1247	Species:	Danio rerio
Sequence 2:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	372	Identity:	76/372 - (20%)
Similarity:	123/372 - (33%)	Gaps:	109/372 - (29%)

- Green bases have known domain annotations that are detailed below.

Zfish    27 LTEHSKSEISHTDREQH-----------VEDR--------NVTSVEDLLQVK-IIPPY------- 64
            :|.:.:..::|...::|           .|||        .||:......|| ::||.
  Fly   101 ITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTS 165

Zfish    65 --ATIEVGQHKQLLCKV-SSDAKNINWVSPNGEKVLTKHGNLKVHNHGSVLSSLTVLNANLNNAG 126
              ..:..|.:..|.||. .|....|.|...:|.|::. :..|:||:..:  .||.:...:..:.|
  Fly   166 SDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVI-NKTLEVHDLET--DSLELERISRLHMG 227

Zfish   127 IYKCVATNG---DTESQATVKLDI------------------------------ILKRMRRDTDR 158
            .|.|:|:||   ....:..|.:|.                              .|....|:.|:
  Fly   228 AYLCIASNGVPPSVSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQ 292

Zfish   159 KGREKRLKEPKPSKKPKASKPTKKPKSEKKGKGEKGGKKKGKKN--REESTTVATTTVAPTTTVP 221
            ...|....:.:......:.|.|.:.........:.|..|...||  .:....:.....:|.||.|
  Fly   293 MITESSKYKTETIPGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQP 357

Zfish   222 MEYEEFYDPEPDQYWDEDFPAETTTVARTTTTPTEKTKDFIPDMDEY-SQPDSYDDYWKVDEPTP 285
                               |..|||:.|||||..|..      :|.| :.|.:.:....|.| .|
  Fly   358 -------------------PPTTTTLRRTTTTAAEIA------LDGYINTPLNGNGIGIVGE-GP 396

Zfish   286 TTSVIAGRPADDDDYWDARSVEMVENLPFPDGKEISSTDN-----DW 327
            |.||||...:         |::.:.||...|..:...|.:     ||
  Fly   397 TNSVIASGKS---------SIKYLSNLNEIDKSKQKLTGSSPKGFDW 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aebp1b	XP_696022.6	Ig	56..147	CDD:299845	25/104 (24%)
		IG_like	62..145	CDD:214653	23/95 (24%)
		FA58C	402..555	CDD:238014
		FA58C	403..556	CDD:214572
		Peptidase_M14_like	577..1036	CDD:299699
		Peptidase_M14NE-CP-C_like	1040..1115	CDD:200604
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	10/53 (19%)
		Ig	69..139	CDD:143165	6/37 (16%)
		IG_like	165..249	CDD:214653	21/86 (24%)
		IGc2	172..237	CDD:197706	19/67 (28%)
		IG_like	267..348	CDD:214653	10/80 (13%)
		Ig	270..339	CDD:299845	10/68 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900