Protein Alignment JPH1 and jph1

DIOPT Version :10

• Sequence 1: NP_065698.1
• Gene: JPH1 / 56704
• HGNCID: 14201
• Length: 661
• Species: Homo sapiens
• Sequence 2: NP_001120224.1
• Gene: jph1 / 100145273
• XenbaseID: XB-GENE-954753
• Length: 560
• Species: Xenopus tropicalis
• Alignment Length: 571
• Identity: 447/571 - (78%)
• Similarity: 486/571 - (85%)
• Gaps: 26/571 - (4%)

Human     1 MTGGRFDFDDGGTYCGGWEEGKAHGHGICTGPKGQGEYSGSWSHGFEVVGGYTWPSGNTYQGYWA 65
            |||||||||||||||||||:||||||||||||||||||||||||||||||.|||||||||.||||
 Frog     1 MTGGRFDFDDGGTYCGGWEDGKAHGHGICTGPKGQGEYSGSWSHGFEVVGAYTWPSGNTYLGYWA 65

Human    66 QGKRHGLGVETKGKWMYRGEWSHGFKGRYGVRQSLCTPARYEGTWSNGLQDGYGVETYGDGGTYQ 130
            |||||||||||||:|:||||||||||||||||||:.|||||:|||||||||||||||||||||||
 Frog    66 QGKRHGLGVETKGRWIYRGEWSHGFKGRYGVRQSMSTPARYDGTWSNGLQDGYGVETYGDGGTYQ 130

Human   131 GQWAGGMRHGYGVRQSVPYGMATVIRSPLRTSLASLRSEQSNGSVLHDAAAAADSPAGTRGGFVL 195
            |||.|||||||||||||||||||||.|||||||:|||||||||:||||  ...|||.|:||||||
 Frog   131 GQWMGGMRHGYGVRQSVPYGMATVIHSPLRTSLSSLRSEQSNGTVLHD--IGVDSPVGSRGGFVL 193

Human   196 NFHADAELAGKKKGGLFRRGSLLGSMKLRKSESKSSISSKRSSVRSDAAMSRISSSDANSTISFG 260
            |||:|:||...||.|||||||||||:|||||:||.||||||||||||||||||||||||||||||
 Frog   194 NFHSDSELMTGKKKGLFRRGSLLGSIKLRKSDSKISISSKRSSVRSDAAMSRISSSDANSTISFG 258

Human   261 DVDCDFCPVEDHVDATTTETYMGEWKNDKRNGFGVSERSNGMKYEGEWANNKRHGYGCTVFPDGS 325
            |.|||:||||||||||||||||||||||||.|||||||||||||||||.||:|||||||:||||:
 Frog   259 DGDCDYCPVEDHVDATTTETYMGEWKNDKRTGFGVSERSNGMKYEGEWLNNRRHGYGCTIFPDGT 323

Human   326 KEEGKYKNNILVRGIRKQLIPIRHTKTREKVDRAIEGAQRAAAMARTKVEIANSRTAHARAKADA 390
            |||||||||:||||||||||||::|||:|||||||||||||||:||||||||.|||.||||||:|
 Frog   324 KEEGKYKNNVLVRGIRKQLIPIKNTKTKEKVDRAIEGAQRAAAVARTKVEIAVSRTEHARAKANA 388

Human   391 ADQAALAARQECDIARAVARELSPDFYQPGPDYVKQRFQEG-VDAKENPEEKVPEKPPTPKESPH 454
            ||||:.|||||.||||||||||||.|:||||:|:||:|||| |:.||:.|||:|:|||:||||||
 Frog   389 ADQASQAARQESDIARAVARELSPSFHQPGPEYIKQKFQEGVVEVKEHIEEKLPQKPPSPKESPH 453

Human   455 FYRKGTTPPRSPEASPKHSHSPASSPKPLKKQNPSSGARLNQ-----DKRSVADEQVTAIVNKPL 514
            ||||||||||:||...|    |||.|.|    ..|.|...|.     .|:|.:.|.:....||||
 Frog   454 FYRKGTTPPRTPEEKRK----PASPPAP----KHSEGKNYNSASAILSKKSSSVENLPISPNKPL 510

Human   515 ----MSKAPTKEAGAVVPQSKYSGRHHIPNPS---NGELHSQYHGYYVKLN 558
                ..|||.||.....|..|.|   ..||||   |||||:.||||.||::
 Frog   511 PFKAPIKAPVKEEVFAPPPPKAS---IAPNPSSTGNGELHADYHGYLVKVS 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JPH1	NP_065698.1	COG4642	<3..333	CDD:443680	294/329 (89%)
		MORN 1	14..36		20/21 (95%)
		MORN 2	38..59		19/20 (95%)
		MORN 3	60..82		19/21 (90%)
		MORN 4	106..128		20/21 (95%)
		MORN 5	129..151		20/21 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	228..247		17/18 (94%)
		MORN 6	281..303		20/21 (95%)
		MORN 7	304..326		18/21 (86%)
		PHA03247	<405..571	CDD:223021	89/167 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	433..631		66/138 (48%)
jph1	NP_001120224.1	COG4642	<3..143	CDD:443680	130/139 (94%)
		PLN03185	38..>323	CDD:215619	253/286 (88%)
		PTZ00449	<334..>538	CDD:185628	134/214 (63%)