DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PSG2 and si:ch211-264f5.6

DIOPT Version :9

Sequence 1:	NP_112536.2	Gene:	PSG2 / 5670	HGNCID:	9519	Length:	335	Species:	Homo sapiens
Sequence 2:	XP_002665524.2	Gene:	si:ch211-264f5.6 / 100319064	ZFINID:	ZDB-GENE-081104-208	Length:	540	Species:	Danio rerio

Alignment Length:	326	Identity:	92/326 - (28%)
Similarity:	131/326 - (40%)	Gaps:	68/326 - (20%)

- Green bases have known domain annotations that are detailed below.

Human    48 GKDVLL--LVHNLPQNLT-GYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGR----ETAYSNA 105
            ||:|..  .|.:.|..|| .:.:.|||...:...|.|    ...:...|.|..|    .|.:
Zfish    36 GKNVTFKTTVVSTPDILTVTWTFNKGQPIAMVTVIPS----SNTVSVRPPYVNRISCNRTTF--- 93

Human   106 SLLIQNVTREDAGSYTLHII-KRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTC 169
            .|.:..:.:||.|.|.|.|: ..||   .|||.....:........|||:.|.|.|...||:|||
Zfish    94 QLQLGPLVKEDTGEYILTIVTNNGD---LVTGQIDLEVLEPVTDVKISSNVLEPVEFNSTVVLTC 155

Human   170 DPETPDTSYQWWMNGQSLPM----TH--------RFQLSETNRTLFLFGVTKYTAGPYECEIRNS 222
            ..:...| |: |:|| |:|:    ||        ..::||..||        ...||..|...|:
Zfish   156 SAKGSFT-YK-WING-SVPLVVDGTHMQLNAVGNELKISEVRRT--------DLQGPIVCIAENA 209

Human   223 GSASRSDPVTLNLLHGPD--LPRIHPSYTNYRSGDNLYLSCFANSNPPAQYSWTING-----KFQ 280
            ..:.:|.|..|.:.:||:  |....|:.|..:.|..|.|:|.|:|||||...|..||     ...
Zfish   210 LESGKSAPFNLTVSYGPENILMNQFPTDTYLKKGSTLTLTCTADSNPPATIQWVFNGVNLPSNAV 274

Human   281 QSGQNLFIPQITTKHSGLYVCSVRN--------------------SATGEESSTSLTVKVSASTR 325
            .|..|..:..:..|:||.|.|...|                    |.|...|||||.:..:::..
Zfish   275 SSPANFTLNNLEEKNSGNYTCVAYNAQTKRYIASRVAFVTVVESLSGTNISSSTSLLIAGNSTVN 339

Human   326 I 326
            :
Zfish   340 L 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PSG2	NP_112536.2	Ig_CEACAM_D1	36..138	CDD:143251	28/97 (29%)
		IG_like	45..>121	CDD:214653	20/79 (25%)
		Ig	148..236	CDD:299845	31/99 (31%)
		Ig_2	242..320	CDD:290606	30/102 (29%)
		IG_like	246..318	CDD:214653	30/96 (31%)
si:ch211-264f5.6	XP_002665524.2	Ig	33..129	CDD:299845	28/102 (27%)
		IG_like	33..128	CDD:214653	28/101 (28%)
		Ig	130..222	CDD:299845	31/102 (30%)
		IG_like	149..222	CDD:214653	25/83 (30%)
		I-set	233..315	CDD:254352	23/81 (28%)
		Ig_2	235..315	CDD:290606	23/79 (29%)
		IGc2	335..398	CDD:197706	0/6 (0%)
		Ig_2	427..494	CDD:290606
		IG_like	427..479	CDD:214653
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D312709at7742
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR44337
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X34
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.980