DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PSG1 and sax-3

DIOPT Version :9

Sequence 1:NP_001284702.1 Gene:PSG1 / 5669 HGNCID:9514 Length:428 Species:Homo sapiens
Sequence 2:NP_001024990.1 Gene:sax-3 / 180637 WormBaseID:WBGene00004729 Length:1273 Species:Caenorhabditis elegans


Alignment Length:438 Identity:89/438 - (20%)
Similarity:148/438 - (33%) Gaps:112/438 - (25%)


- Green bases have known domain annotations that are detailed below.


Human    25 LNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYITSYVVDGEII 89
            ||....|:||::|                             |||               ||:  
 Worm    50 LNCGAKPSTAKIT-----------------------------WYK---------------DGQ-- 68

Human    90 IYGPAYSGRETAYSNASLLIQNVTREDAGS-YTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISS 153
               |..:.:|...|:..:|       |.|| :.|.:..|.:|.....|.:......|..:...:.
 Worm    69 ---PVITNKEQVNSHRIVL-------DTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNE 123

Human   154 SNL-----------NPRETMEAVS-----LTCDPET--PDASYLWWMNGQSLPMTHSLKLS-ETN 199
            .:|           .|| |::|:.     |.|.|..  |:....|..:.:.|.:....:.: .::
 Worm   124 GSLKLAMLREDFRVRPR-TVQALGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSD 187

Human   200 RTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDV------- 257
            ..|.:..|.:..:|.|:|...|.|....|:|..|::..| ||        ..:|.||:       
 Worm   188 GNLIIDPVDRSDSGTYQCVANNMVGERVSNPARLSVFEK-PK--------FEQEPKDMTVDVGAA 243

Human   258 LNFTCEPKSENYTYIWW-LNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRS 321
            :.|.|....:....|.| ...:.:||: |.....:||.|.:..|..::.|.|.|..|:..|.:.:
 Worm   244 VLFDCRVTGDPQPQITWKRKNEPMPVT-RAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEA 307

Human   322 DPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQL------------ 374
            . ..|.|...|.. :..|:.....:|......|:....|...|.|:...:..|            
 Worm   308 S-AHLRVQAPPSF-QTKPADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRT 370

Human   375 ---PGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSAYSSS 419
               |...|.|..:.....|.|||:..|||....|..::.|...|.:.:
 Worm   371 KVSPTGTLTIEEVRQVDEGAYVCAGMNSAGSSLSKAALKVTTKAVTGN 418

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PSG1NP_001284702.1 Ig_CEACAM_D1 36..138 CDD:143251 17/102 (17%)
IG_like 41..>121 CDD:214653 12/80 (15%)
Ig 148..236 CDD:299845 21/106 (20%)
IG_like 163..221 CDD:214653 12/65 (18%)
Ig 241..329 CDD:299845 21/95 (22%)
IG_like 256..328 CDD:214653 18/79 (23%)
Ig_2 335..413 CDD:290606 19/92 (21%)
IG_like 339..413 CDD:214653 19/88 (22%)
sax-3NP_001024990.1 Ig 30..129 CDD:299845 24/134 (18%)
I-set 31..121 CDD:254352 23/126 (18%)
I-set 135..223 CDD:254352 20/88 (23%)
Ig2_Robo 137..223 CDD:143201 20/86 (23%)
I-set 227..313 CDD:254352 22/95 (23%)
Ig 244..313 CDD:299845 17/70 (24%)
I-set 317..410 CDD:254352 19/93 (20%)
Ig 331..411 CDD:299845 17/79 (22%)
Ig 424..512 CDD:299845
I-set 432..512 CDD:254352
FN3 531..624 CDD:238020
FN3 659..747 CDD:238020
FN3 755..836 CDD:214495
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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