Protein Alignment PSG1 and lad-2

DIOPT Version :9

• Sequence 1: NP_001284702.1
• Gene: PSG1 / 5669
• HGNCID: 9514
• Length: 428
• Species: Homo sapiens
• Sequence 2: NP_001023496.1
• Gene: lad-2 / 177078
• WormBaseID: WBGene00002243
• Length: 1187
• Species: Caenorhabditis elegans
• Alignment Length: 452
• Identity: 100/452 - (22%)
• Similarity: 157/452 - (34%)
• Gaps: 125/452 - (27%)

Human     4 LSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWY 68
            :|..|....::..|.|....:.....|||.....|:.|                ||
 Worm   240 MSVSPSEVTVRAGGQLKLQCIFGGRPLPTIFWSKIDGE----------------LP--------- 279

Human    69 KGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRG 133
            |.:::||    ||:..|          .||       ||:::||..:|||:|.   .:|......
 Worm   280 KSRIKDL----TSHESD----------FGR-------SLIVENVHPDDAGAYE---CRGRHLVHT 320

Human   134 VTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSET 198
            |..|.......|...|  ...:|....|.|...|.....||..:  |.|||:.|   |  :|:|.
 Worm   321 VNVRVMAAPFWEFDPP--RDISLPEESTGELECLAGGQPTPIIT--WSMNGKFL---H--ELAED 376

Human   199 NRTLFL-----LGVTKYT----AGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNL----- 249
            :|.:.|     |.|....    .|.|:|...||:.                  |:..|..
 Worm   377 SRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLG------------------YVFANAFVHVRA 423

Human   250 --------NPRENKDVLNFT----CEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPS--- 299
                    ..|..|.||:.|    |:..:.....:.|::....|:     :.:|.:..:.|:
 Worm   424 HAPFFRMPAARHWKVVLHSTVVLDCDVDAAPEAMVRWVDADDRPL-----QVVEGKNKLFPNHTF 483

Human   300 ----VTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRI-YPSFTYYRSGEVLYLSCSADSN 359
                |...:.|.|.|.:.::| ||......|.|.......|| .|......:||...:.|.|.::
 Worm   484 MVYDVNSADEGLYYCNVSNKY-GINRATNRLQVFKPTYFVRIPTPKRLILEAGETAEVFCEAVAD 547

Human   360 P--PAQYSWTINEK-------FQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVE 412
            |  |.:|.||||.|       :::...:|..|.:..:|||:..|:.......|.:|..:.|:
 Worm   548 PRLPIRYQWTINGKVLTESQYYEILPDRLRFRSVRGRHSGIIDCAAITDVDVKLASMQLIVK 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PSG1	NP_001284702.1	Ig_CEACAM_D1	36..138	CDD:143251	22/101 (22%)
		IG_like	41..>121	CDD:214653	18/79 (23%)
		Ig	148..236	CDD:299845	24/96 (25%)
		IG_like	163..221	CDD:214653	19/66 (29%)
		Ig	241..329	CDD:299845	20/111 (18%)
		IG_like	256..328	CDD:214653	16/82 (20%)
		Ig_2	335..413	CDD:290606	24/88 (27%)
		IG_like	339..413	CDD:214653	22/83 (27%)
lad-2	NP_001023496.1	IG_like	48..116	CDD:214653
		Ig	49..121	CDD:299845
		Ig	124..214	CDD:299845
		IG_like	244..325	CDD:214653	28/129 (22%)
		Ig	255..325	CDD:299845	26/118 (22%)
		I-set	335..421	CDD:254352	26/112 (23%)
		Ig4_L1-NrCAM_like	344..422	CDD:143179	24/102 (24%)
		IG_like	438..515	CDD:214653	16/82 (20%)
		Ig	443..516	CDD:299845	14/78 (18%)
		IG_like	527..608	CDD:214653	21/80 (26%)
		Ig	535..>593	CDD:299845	18/57 (32%)
		FN3	610..697	CDD:238020	100/452 (22%)
		FN3	721..804	CDD:238020
		fn3	823..909	CDD:278470
		FN3	921..1010	CDD:238020
		FN3	1016..1108	CDD:238020

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910