DRSC/TRiP Functional Genomics Resources

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Protein Alignment SUCNR1 and npr-22

DIOPT Version :9

Sequence 1:NP_149039.2 Gene:SUCNR1 / 56670 HGNCID:4542 Length:334 Species:Homo sapiens
Sequence 2:NP_001023541.1 Gene:npr-22 / 190424 WormBaseID:WBGene00022004 Length:434 Species:Caenorhabditis elegans


Alignment Length:356 Identity:79/356 - (22%)
Similarity:149/356 - (41%) Gaps:82/356 - (23%)


- Green bases have known domain annotations that are detailed below.


Human    24 YYLS--------IFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDL--AFLCTLP- 77
            |:|:        :||.|..|..|.||.:|:...::..:...::||.:.||:|:||  :..| :| 
 Worm    43 YHLTPSMKMLCILFYSILCVCCVYGNVLVILVIVYFKRLRTATNILILNLAVADLLISVFC-IPF 106

Human    78 ----MLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEF 138
                :||  |.:..|::|.::|....::....::.|...|..||.||::.|.:....::...:..
 Worm   107 SYWQVLI--YDDQRWLFGSMMCSLLAFLQAMAVFLSAWTLVVISFDRWMAIMFLLTPNIRITRRR 169

Human   139 AILISLAIWVLVTLELLPILPLINPVITDNG-TTCND----FASSGDPNYNLIYSMCLTLLGFLI 198
            |:.:..|.|:...|..||:|.........:| ..|.:    |..||: ....:||..:.:|.:::
 Worm   170 ALYLVAATWIFSILMALPLLFTTRFFEDQDGLPNCGENWTYFGDSGE-QVRKVYSSMVLILQYVV 233

Human   199 PLFVMCFFYYKIAL-----------------FLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFT 246
            |..|:...|..|.:                 .:..|:..|...:|      :||:...:|::.:.
 Worm   234 PQAVLIITYTHIGIKMWNSRVPGMQNGATKKMIVDRHESVKKLVP------MVILISALFALCWL 292

Human   247 PYHVMRNV--RIASRLGSWKQYQCTQVVINSFYIV-----TRPLAFLNSVINPVFYFLLGDHFRD 304
            |..::.||  .....:.||.            ||:     ...||..:|::||:.||:....||:
 Worm   293 PLLILINVIPEFYPDINSWG------------YILYLWWFAHGLAMSHSMVNPIIYFIRNARFRE 345

Human   305 MLMNQLRHNFKSLTSFSRWAHELL--LSFRE 333
                          .|..::.:||  :||:|
 Worm   346 --------------GFCFFSSKLLPCISFKE 362

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SUCNR1NP_149039.2 7tmA_SUCNR1_GPR91 24..306 CDD:320500 73/325 (22%)
TM helix 1 24..51 CDD:320500 10/34 (29%)
TM helix 2 58..83 CDD:320500 11/31 (35%)
TM helix 3 95..125 CDD:320500 7/29 (24%)
TM helix 4 137..159 CDD:320500 6/21 (29%)
TM helix 5 184..213 CDD:320500 7/45 (16%)
TM helix 6 225..255 CDD:320500 7/31 (23%)
TM helix 7 274..299 CDD:320500 9/29 (31%)
npr-22NP_001023541.1 7tmA_PR4-like 51..347 CDD:320514 71/331 (21%)
TM helix 1 52..78 CDD:320514 8/25 (32%)
TM helix 2 85..110 CDD:320514 9/25 (36%)
TM helix 3 126..156 CDD:320514 7/29 (24%)
TM helix 4 169..190 CDD:320514 6/20 (30%)
TM helix 5 219..248 CDD:320514 7/28 (25%)
TM helix 6 271..301 CDD:320514 7/35 (20%)
TM helix 7 315..340 CDD:320514 7/24 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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