DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SUCNR1 and npr-25

DIOPT Version :9

Sequence 1:NP_149039.2 Gene:SUCNR1 / 56670 HGNCID:4542 Length:334 Species:Homo sapiens
Sequence 2:NP_505883.1 Gene:npr-25 / 179570 WormBaseID:WBGene00011381 Length:376 Species:Caenorhabditis elegans


Alignment Length:340 Identity:88/340 - (25%)
Similarity:153/340 - (45%) Gaps:49/340 - (14%)


- Green bases have known domain annotations that are detailed below.


Human    27 SIFYGIEFVVGVLGNTIVVYGYIF----SLKN----WNSSNIYLFNLSVSDLAFLCTLPMLIRSY 83
            :|.|.|.||.|.||||.|: .|:|    |||:    ..::.||:..|...||....::|..:...
 Worm    24 AIPYSICFVFGTLGNTAVL-SYVFFITRSLKSSVTALGNTFIYIVALCAVDLLVTVSIPFSLSYM 87

Human    84 ANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWV 148
            ...||::|:::|..:..:..:|...|...||.::.|||:.|.:|..:.:.:.:....:.:    :
 Worm    88 ILNNWVFGELVCKIHFMLELSNKMCSTFILTALAFDRYMAICHPEIKRIHEMRHTIYITT----I 148

Human   149 LVTLELLPILPLINPVITDNGTTC----NDFASSGDPNYNLIYSMC---------------LTLL 194
            |.||.|.    ||:||:.....|.    ..|.|:.:..:.:|..||               |...
 Worm   149 LATLSLF----LISPVVLSARVTSFKSGQYFVSAKNERHEVIRQMCIDGMALEWKVWVSAFLIFF 209

Human   195 GFLIPLFVMCFFYYKIALFL-KQRNRQVATALPLEKPLNLVIMAVVIFSV-LFTPYHVMRNVRIA 257
            .||:|..::.:||.||.|.| :||...:.:.:||.: :.:..||...|.: ...|:.:.:...|.
 Worm   210 AFLLPCTLLTYFYAKIVLRLRRQRRTMLQSRIPLRR-ITIYTMAATFFYLSCHIPFWLPQIYNIF 273

Human   258 SRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLM----NQLRHNFKSL- 317
            |.:...|..  .:|:..::|  :..|.|:::..|.:||..|...|:..|:    ..:|...||: 
 Worm   274 STVLGHKMN--PKVMTFTYY--SHLLPFISAAFNWIFYARLNSQFKKGLVLVTERMIRKRTKSMH 334

Human   318 -TSFSRWAHELLLSF 331
             ..:|..|.||...|
 Worm   335 EKGYSEAAVELTSKF 349

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SUCNR1NP_149039.2 7tmA_SUCNR1_GPR91 24..306 CDD:320500 79/307 (26%)
TM helix 1 24..51 CDD:320500 13/27 (48%)
TM helix 2 58..83 CDD:320500 6/24 (25%)
TM helix 3 95..125 CDD:320500 8/29 (28%)
TM helix 4 137..159 CDD:320500 4/21 (19%)
TM helix 5 184..213 CDD:320500 11/43 (26%)
TM helix 6 225..255 CDD:320500 6/30 (20%)
TM helix 7 274..299 CDD:320500 6/24 (25%)
npr-25NP_505883.1 7tm_classA_rhodopsin-like 24..311 CDD:381740 77/300 (26%)
TM helix 1 24..48 CDD:381740 13/24 (54%)
TM helix 2 63..84 CDD:381740 6/20 (30%)
TM helix 3 100..122 CDD:381740 4/21 (19%)
TM helix 4 144..160 CDD:381740 6/23 (26%)
TM helix 5 200..223 CDD:381740 5/22 (23%)
TM helix 6 244..269 CDD:381740 4/25 (16%)
TM helix 7 286..311 CDD:381740 6/26 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

Return to query results.
Submit another query.