DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SUCNR1 and LOC100485245

DIOPT Version :9

Sequence 1:	NP_149039.2	Gene:	SUCNR1 / 56670	HGNCID:	4542	Length:	334	Species:	Homo sapiens
Sequence 2:	XP_004914933.1	Gene:	LOC100485245 / 100485245	-ID:	-	Length:	323	Species:	Xenopus tropicalis

Alignment Length:	314	Identity:	176/314 - (56%)
Similarity:	235/314 - (74%)	Gaps:	2/314 - (0%)

- Green bases have known domain annotations that are detailed below.

Human    13 NWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLP 77
            |....|:.|:||||...|.||||:|::||.|.::||.|.||||:|.::|||||.:||.|||||||
Frog    10 NCTDTESFLKKYYLPAAYTIEFVIGLIGNCIALFGYFFCLKNWSSGSVYLFNLCISDFAFLCTLP 74

Human    78 MLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILI 142
            ||:.||.:..|.:||.||..|||:||.||||.||||.|||||||::||||||||:||:|..|::|
Frog    75 MLVFSYIHEEWTFGDFLCKCNRYLLHENLYTGILFLAFISIDRYMLIKYPFREHILQRKSTAMMI 139

Human   143 SLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFY 207
            ||.||:||:||:.|||..:...|.:|.|.|.|||||.|...||:||:|||..||:|||.|:..||
Frog   140 SLGIWILVSLEISPILIFLKQDIINNVTICPDFASSADATGNLVYSLCLTFTGFIIPLCVIWIFY 204

Human   208 YKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCTQVV 272
            .|:..|||.||:|:......:||:.:|::|..:||:.|||:|||||||:|||:.||....|:.::
Frog   205 LKMMCFLKNRNQQLPNRASFKKPVIIVVLAATMFSIFFTPFHVMRNVRLASRIESWTLSGCSSII 269

Human   273 INSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSF--SRWA 324
            |:|.||:::|:.||||:||||||||:|||||:||:.:::..:|||...  ||||
Frog   270 ISSAYIISKPILFLNSMINPVFYFLMGDHFREMLLAKIQRIYKSLKCIFNSRWA 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SUCNR1	NP_149039.2	7tmA_SUCNR1_GPR91	24..306	CDD:320500	163/281 (58%)
		TM helix 1	24..51	CDD:320500	14/26 (54%)
		TM helix 2	58..83	CDD:320500	16/24 (67%)
		TM helix 3	95..125	CDD:320500	21/29 (72%)
		TM helix 4	137..159	CDD:320500	12/21 (57%)
		TM helix 5	184..213	CDD:320500	16/28 (57%)
		TM helix 6	225..255	CDD:320500	14/29 (48%)
		TM helix 7	274..299	CDD:320500	16/24 (67%)
LOC100485245	XP_004914933.1	7tm_1	37..292	CDD:278431	145/254 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	335	1.000	Domainoid score	I7930
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41865
Inparanoid	1	1.050	384	1.000	Inparanoid score	I9314
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG38906
OrthoDB	1	1.010	-	-		D1133445at2759
OrthoFinder	1	1.000	-	-		FOG0007550
OrthoInspector	1	1.000	-	-		otm55100
Panther	1	1.100	-	-	O	PTHR24231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5668
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080