DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SUCNR1 and oxgr1a.3

DIOPT Version :9

Sequence 1:	NP_149039.2	Gene:	SUCNR1 / 56670	HGNCID:	4542	Length:	334	Species:	Homo sapiens
Sequence 2:	NP_001139100.1	Gene:	oxgr1a.3 / 100005578	ZFINID:	ZDB-GENE-090312-23	Length:	329	Species:	Danio rerio

Alignment Length:	314	Identity:	107/314 - (34%)
Similarity:	172/314 - (54%)	Gaps:	8/314 - (2%)

- Green bases have known domain annotations that are detailed below.

Human     8 NATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAF 72
            |.:..|....:..:::|||...|.|..|||.:||...:..::..::.|.||.|.:.||..:||..
Zfish    11 NTSNDNCTDVDNLVKRYYLPTMYAIICVVGAIGNITALLVFVLRIRPWRSSTIIMVNLIFTDLLL 75

Human    73 LCTLPMLIRSYA-NGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKK 136
            :.:||:.:..|. |.:|..|..:|..:|:..|.|||.|||.||.||:.||::|.:|.....:.:|
Zfish    76 IISLPIFVYYYVLNDSWTLGITMCRFSRFDFHFNLYGSILALTCISVIRYVVIVHPQHAENISRK 140

Human   137 EFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLF 201
            .:.|:..:..|::..:||.||..|...|..||.|.|.||||: ||.....||..||:||||:||.
Zfish   141 RWGIMSCMLFWIITVVELSPIFNLFATVEIDNKTYCLDFASN-DPQSVWPYSWVLTVLGFLVPLV 204

Human   202 VMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQY 266
            |:|..|::|...||:.....:|:..|.:  .::::.:..|:|.|.||||:|..|:.:||  ..:.
Zfish   205 VVCVCYWRIIEKLKEGPHTGSTSRLLAR--RVIVLIITCFAVCFLPYHVLRAFRVYTRL--TPET 265

Human   267 QC-TQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLR-HNFKSLT 318
            .| ....:::.||::||:|.||.:.|.|.|.:.|.:|:...:...: ...||.|
Zfish   266 NCMLDHGVHAAYIISRPIAVLNIIFNMVLYTMQGGNFKQAFVELFKCKKLKSKT 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SUCNR1	NP_149039.2	7tmA_SUCNR1_GPR91	24..306	CDD:320500	102/283 (36%)
		TM helix 1	24..51	CDD:320500	10/26 (38%)
		TM helix 2	58..83	CDD:320500	8/24 (33%)
		TM helix 3	95..125	CDD:320500	15/29 (52%)
		TM helix 4	137..159	CDD:320500	6/21 (29%)
		TM helix 5	184..213	CDD:320500	14/28 (50%)
		TM helix 6	225..255	CDD:320500	9/29 (31%)
		TM helix 7	274..299	CDD:320500	10/24 (42%)
oxgr1a.3	NP_001139100.1	7tm_1	43..295	CDD:278431	91/256 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.870