Protein Alignment atp8b3 and CG33298

DIOPT Version :9

• Sequence 1: XP_003201102.2
• Gene: atp8b3 / 566530
• ZFINID: ZDB-GENE-050208-424
• Length: 1174
• Species: Danio rerio
• Sequence 2: NP_995666.1
• Gene: CG33298 / 2768929
• FlyBaseID: FBgn0032120
• Length: 1517
• Species: Drosophila melanogaster
• Alignment Length: 1307
• Identity: 392/1307 - (29%)
• Similarity: 605/1307 - (46%)
• Gaps: 266/1307 - (20%)

Zfish    56 GRYADNVVRSYKYTPLTFFPLNLYEQFQRAANLFFLLIVILQCVPVIATIPWYTTMLPLLIVLFV 120
            |::..|.:|:.|||.|:|.|.||.|||.|.|||:|:.||:|..||.|:.......|:|:|.||.|
  Fly   248 GQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGV 312

Zfish   121 RGCKDLATDVGRRRSDAQINRRPCDIL--TPEGFKTVKWKDVCVGDILRVHKDQVIPADLLLLCS 183
            ...|||..|..||.||.:||...|.:.  ..|.:|.|||:::.||||:.:..::.:|||:|||.:
  Fly   313 TAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRT 377

Zfish   184 TEPYSLCYVETADIDGETNLKFRQALTVTHTELNGDSTEQNL---AAFDAIVRCEEPNGNLHSFR 245
            ::|..:||::|.|:|||||||.|:.       :.|....|::   :.|.:.|..:.|...|:.|.
  Fly   378 SDPQGVCYIDTCDLDGETNLKRREV-------VRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFH 435

Zfish   246 GE-FHWKGERHLLGTDHLLLRGTVLRNTDYAYGLTIYTGSDSKILQNCGRLKLKKTHVEILLNKT 309
            |. .|..|||..:.|:.||||.:.|:||||..|:.:|.|.::|.:.|....:.|::.||..:|..
  Fly   436 GALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNID 500

Zfish   310 VLVILLFMLTTALLLAIGAGIFEYRISPNYDVVSIVQRDSSPAYQGFLTFWGYIILLSPSMPMSL 374
            |:..::.:|...::.|||..::....: ::.|..:.....:...:....||.||::|...:|:||
  Fly   501 VIWCVIILLILCVVGAIGCRMWLSSFT-HFPVPYLPPNKLTANMESMWIFWTYIVILQVMIPLSL 564

Zfish   375 YITFEVIHMVHCLLIGWDVEMYWEDTNCPAHARTTTLNEELGQVGHLLSDKTGTLTQNRLLFRQC 439
            |:|.|:..::....|..:|:::..:||.....|...:.|||||:.|:.:|||||||:|:::||:|
  Fly   565 YVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRC 629

Zfish   440 FIAGHIYGDISQK-----SKP------------LDLSWNRFSCGG-LKFSDQRLVDKLRGRGSLE 486
            .:.|..|.....:     |||            |:....:.:.|. |....||:
  Fly   630 VVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRI----------- 683

Zfish   487 CQEFFTALALCHTVM-------------------------------------------------- 501
             |||...||:|:||:
  Fly   684 -QEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTI 747

Zfish   502 ------------------------------------------------------------SEWK- 505
                                                                        ||.:
  Fly   748 INGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPNSESES 812

Zfish   506 ----------------------------------------------------------DGLPHYQ 512
                                                                      ||.|.|:
  Fly   813 PSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYRTADGRPLYE 877

Zfish   513 AASPDEEALVCAARELGWVFLSRTRDTLTIS--EMGLTRNYQLLALLDFTSKRRRMSVLVRSPGG 575
            |.||||.|||.||.......|:|:.:.:.:|  ..|.||.|::|.:|.|.|.|:.||::||..|.
  Fly   878 AESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGS 942

Zfish   576 Q-LKLYSKGADIVILERL------QKDWPLQESTDRALELFAQSCLRTLCVAVRPVPEALWTEWS 633
            | :.||:||||..|:..|      ..:..|:|.|.:.|:.:|:..||.|.:|.|.:..|.:|:|.
  Fly   943 QEIVLYTKGADSSIMPVLVPCSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWW 1007

Zfish   634 RALNLAGTATGNQETLLEEIYDQMEKDLMLLGVTAIEDRLQEGVPETIASLRRAGVKVWVLTGDK 698
            ........:..|:|..|.:.:.::|.:|.|||.|.||||||:|||||||||..||:.||||||||
  Fly  1008 ARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDK 1072

Zfish   699 TETAVNVGYACKLMDPDTTLIQGEELRQLLESPSSNVDVKSKEPEVWITD--------------- 748
            .|||:|:.|:.||.         .:..:|:...:.:.|........::||
  Fly  1073 PETAINIAYSAKLF---------TQQMELIRLTARSRDAAETAINFYLTDMENDKTTSTLGYGQS 1128

Zfish   749 --KKAVMSKAALVISGPELA-ELTKSSEWGAKFVALSGQCQSVLCCRVTPAQKAEVVEMVRKHSA 810
              ||    :.|||:.|..|. .|...|:....|:.||.:|.||||||.||.|||.:|::|::...
  Fly  1129 LRKK----QRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELN 1189

Zfish   811 SITMAIGDGANDVNMIKTAHIGVGLCGVEGSQAVLNADFALAQFSFLRKLLLVHGHWSYYRISIL 875
            ..|:|||||||||:||:.|.:|||:.|.||.|||:.|||.|.:|.:|.:|||.||:|.|.|:|.:
  Fly  1190 LRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRM 1254

Zfish   876 LRYFLYKTTAFALVHTWYSFYNGFSAQPMYESWYISLFTTTYTSLPIQCTGIFEQDISARSCLCW 940
            :.||.||..||..:..||..|.|||.|.|.:..|:.|:...:||||....|::::.::....|..
  Fly  1255 ILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKN 1319

Zfish   941 PEIYSIGQKKQLFNPSVLASTLLYSFYSSIIFFFVPMGILQYSALDFQTLAITIETSVLFATTLE 1005
            |.:|..|:....:.|......||.:.|.|::.|||.:.....|.:.......||..|.|||..:.
  Fly  1320 PYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVH 1384

Zfish  1006 VILCTKYWTKWNVAAVIFSLAAFFLSTLALHSTRLFTASPK-DYFFLGASQNAYSTPEVWLTIFV 1069
            ..:..:.||..:|.:::.||.:|:|..:...|..:.....: .|:.:..   .:::...||.|.:
  Fly  1385 CAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIFV---CFASAVHWLVIML 1446

Zfish  1070 TTCVAVLPSITTRALGVVLANPNKHKI------HSSANEPVELQSWFQRGTVQRRSSYAVSQGKG 1128
            :|.|||||.:....:.:.|...:..|:      ..|..|.: |.:| .|.| ...|.|.::....
  Fly  1447 STVVAVLPRLLLTTVRISLCPDDSTKVILQSKRERSRGEAL-LVTW-SRST-SASSIYRITDYGS 1508

Zfish  1129 FGKLITT 1135
            ..::|||
  Fly  1509 KNQIITT 1515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
atp8b3	XP_003201102.2	PhoLip_ATPase_N	52..109	CDD:292826	25/52 (48%)
		ATPase-Plipid	58..1096	CDD:273734	379/1258 (30%)
		Cation_ATPase	<515..591	CDD:289987	34/78 (44%)
		R3H	650..706	CDD:294210	36/55 (65%)
		HAD_like	<813..837	CDD:304363	16/23 (70%)
		PhoLip_ATPase_C	844..1084	CDD:292829	74/240 (31%)
CG33298	NP_995666.1	PhoLip_ATPase_N	249..299	CDD:292826	24/49 (49%)
		ATPase-Plipid	250..1473	CDD:273734	379/1258 (30%)
		E1-E2_ATPase	302..>394	CDD:278548	38/91 (42%)
		Cation_ATPase	<880..965	CDD:289987	35/84 (42%)
		HAD_like	<1177..1240	CDD:304363	32/62 (52%)
		PhoLip_ATPase_C	1223..1468	CDD:292829	75/247 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53737
OrthoDB	1	1.010	-	-		D587717at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830