Protein Alignment rnf145a and rnf145

DIOPT Version :10

• Sequence 1: XP_005157379.1
• Gene: rnf145a / 565986
• ZFINID: ZDB-GENE-111012-3
• Length: 649
• Species: Danio rerio
• Sequence 2: NP_001072260.1
• Gene: rnf145 / 779713
• XenbaseID: XB-GENE-979193
• Length: 695
• Species: Xenopus tropicalis
• Alignment Length: 656
• Identity: 534/656 - (81%)
• Similarity: 580/656 - (88%)
• Gaps: 18/656 - (2%)

Zfish     1 MAVKERVEAVLNVGLRVPSIMLLEVLYRWDVSSFFQKIQRSSLNNNPLFQYKYLALYLHYVGYIL 65
            |..||::||:|||.|||||||||:|||||||||||::|||||||||||||||||||.:|||||||
 Frog     1 MGAKEKLEAMLNVALRVPSIMLLDVLYRWDVSSFFKQIQRSSLNNNPLFQYKYLALNMHYVGYIL 65

Zfish    66 SLVLLTLPRQHLVQLYLYVLTALLLFAGHQISRDYVRSELESGYEGPLYLEPLSINRFTTALLCQ 130
            |:||||||||||.:||||.:.||||:|||||||||||||||||||||:::||||:|||.|||:.|
 Frog    66 SVVLLTLPRQHLAKLYLYFVAALLLYAGHQISRDYVRSELESGYEGPMHIEPLSMNRFITALVGQ 130

Zfish   131 LVVCTLCSCVMQTKRIWLFSAHLLPLVARLCLVPLETIVFVNRFAMIFTGLEVIYFLASNLLVPF 195
            |||||||||||:||:|||||||:|||:|||||||:||||.:|:||||||||||:|||||||||||
 Frog   131 LVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPIETIVVINKFAMIFTGLEVLYFLASNLLVPF 195

Zfish   196 NLAKTAYRELAQVVEVYGLLALGMSLWNQLVLPVLFMCFWLVLFALQIYTYFSTRDQPTSRERLL 260
            ||||:||||||||||||||||||||||||||:|||||.|||||||||||||||||||||||||||
 Frog   196 NLAKSAYRELAQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYTYFSTRDQPTSRERLL 260

Zfish   261 FLFLTSIAECCCTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDNTMHRGMTEGITLLILA 325
            |||||||||||.||||||||||||||||||||||||||||||||||||..|:||||||:||||||
 Frog   261 FLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILA 325

Zfish   326 VQTGLIELQVIHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 390
            ||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   326 VQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 390

Zfish   391 VFPAYMSYMICQFFHMDFWLLIIISSSILTSLQVLGTLLIYVLFMVEELRKAPVENMDDVIYWVN 455
            |||:||:|||||||||||||||||||||||||||||||.||||||:||.||.||||||||||:||
 Frog   391 VFPSYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMIEEFRKEPVENMDDVIYYVN 455

Zfish   456 GTYRLLEFLVALCVVAYGVSETVFGEWTVMGSTIVLIHSYYNVWLRAQLGWQSFLLRRDAVNKIK 520
            ||||||||||||||||||||||||||||||||.|:.|||||||||||||||:|||||||||||||
 Frog   456 GTYRLLEFLVALCVVAYGVSETVFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIK 520

Zfish   521 SLPTASLQQLQQHNDICSICYQDMTSAVITPCSHLFHAGCLKKWLYVQETCPLCHNQLKGSSQ-- 583
            |||.|:.:||:|||||||||||||.|||||||||.||.|||||||||||||||||.|||..||
 Frog   521 SLPVATKEQLEQHNDICSICYQDMNSAVITPCSHFFHPGCLKKWLYVQETCPLCHCQLKSLSQQA 585

Zfish   584 ---LGSSSQDV-------PPQDTPAQPEEDQDPSEPADSESNLQ-----DLRQDDSSTRAPASEL 633
               .|||:..|       ||....::.|...:|.....:.|.|:     |::. ..|......||
 Frog   586 TGESGSSTNPVSEQSATNPPLGPVSRAEVTTEPLAAVPTRSALEQEPTMDIKV-SGSVEKRIGEL 649

Zfish   634 RARLKQ 639
            .|...|
 Frog   650 EAHFSQ 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf145a	XP_005157379.1	TRC8_N	8..506	CDD:463960	448/497 (90%)
		rad18	523..>648	CDD:273165	66/134 (49%)
		RING_Ubox	533..575	CDD:473075	38/41 (93%)
rnf145	NP_001072260.1	TRC8_N	8..506	CDD:463960	448/497 (90%)
		RING-H2_RNF145	533..575	CDD:319598	38/41 (93%)
		rad18	537..>651	CDD:273165	55/114 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	585..610		6/24 (25%)