Protein Alignment rnf145a and rnf-145

DIOPT Version :9

• Sequence 1: XP_005157379.1
• Gene: rnf145a / 565986
• ZFINID: ZDB-GENE-111012-3
• Length: 649
• Species: Danio rerio
• Sequence 2: NP_491382.2
• Gene: rnf-145 / 172053
• WormBaseID: WBGene00022471
• Length: 742
• Species: Caenorhabditis elegans
• Alignment Length: 656
• Identity: 192/656 - (29%)
• Similarity: 338/656 - (51%)
• Gaps: 60/656 - (9%)

Zfish     3 VKERVEAVLNVGLRVPSIMLLEVLYRWDVSSFFQKIQRSSLNNNPLFQY---------------K 52
            :||....||..|||:|.::.:|:|:|:...| |:.|....:...||..:               .
 Worm    44 IKEMSIMVLETGLRLPGLLFIELLWRYQGFS-FEDISDDMMKQTPLSYFDIPTMLDFVHRRNFDH 107

Zfish    53 YLALYLHYVGYILSLVLLTLPRQHLVQLYLYVLTALLLFAGHQISRDYVRSELESGYEGPLYLEP 117
            :.|:.|.|....:||:.||||...|:::|.:.|:..|....:::|..||..|:::| |..|.|:.
 Worm   108 HAAIILSYFVIFISLMFLTLPLSRLIRMYSHFLSVFLFGVAYKLSAIYVDLEMKTG-EEELKLDG 171

Zfish   118 L-SINRFTTALLCQLVVCTLCSCVMQTK----RIWLFSAHLLPLVARLCLVPLETIVFVNRFA-- 175
            | .:.|.....|.|:::..|.|.:::..    |:.| ....||:|||:|..|::.:...:.:|
 Worm   172 LIKLERHGFHFLAQMLLVVLQSMLLEVDGEPWRVAL-PVFALPIVARMCGCPMDKLKNAHNYACT 235

Zfish   176 --MIFTGLEVIYFLASNLLVPFNLAKTAYRELAQVVEVYGLLALGMS-LWNQLVLPVLFMCFWLV 237
              |||....::| .|.:|:   ...|||.|::..|..|:| ||.|:: ||.:|.:..|....|:.
 Worm   236 GTMIFIATYMLY-RAPSLI---KSTKTALRQIKAVFMVHG-LADGVAVLWRKLRILELLTFTWIT 295

Zfish   238 LFALQIYTYFSTRDQPTSR-ERLLFLFLTSIAECCCTPYSLLGLVFTVSFVALGVLTLCKFYLQG 301
            :|.:.:|.....:.:..|. .|:|   ||.:||...||.:|..|..:||:|...:..|.|....|
 Worm   296 MFLMVLYVELIDKGRTWSEVGRIL---LTGVAETTNTPITLAALAVSVSYVCKWIADLTKLITGG 357

Zfish   302 YRAFMNDNTMHRGMTEGITLLILAVQTGLIELQVIHRAFLLSIILFIVVASILQSMLEIADPIVL 366
            .|:. .....|.|.||.::::||.:|||.:.:||..:..||:::|:||::::|||:.||.:.::|
 Worm   358 TRSH-GHVLAHSGYTEAVSVVILCIQTGFLGMQVEQKTILLALVLYIVISALLQSLFEIIEVVLL 421

Zfish   367 ALGASRDKSLWKHFRAVSLCLFLLVFPAYMSYMICQFFHMDFWLLIIISSSILTSLQVLGTLLIY 431
            .|.:|...|..:|.|.:.:.|.|:|.|.:.:..:.....:|.:..|||::|...:.:.:|.:|.|
 Worm   422 NLPSSPTASRARHARCICIALLLVVIPFFTTKTMLALLPIDIYTAIIIANSATVTARAIGVILKY 486

Zfish   432 VLFMVEELRKAPVENMDDVIYWVNGTYRLLEFLVALCVVAYGVSETVFGEWTVMGSTIVLIHSYY 496
            ::.:||...:.|.|.:||:.|:::...:.:|.|.|..|:.:|..:.|...::.....|:|.|...
 Worm   487 IVLIVETKSEEPWEGIDDLTYYIDCANKGIELLAAKVVMVFGCMQVVKVGFSFATFAILLFHVIV 551

Zfish   497 NVWLRAQLGWQSFLLRRD-AVNKIKSLPTASLQQLQQHNDICSICYQDM-TSAVITPCSHLFHAG 559
            |::.|.: ...||:..|: ||..|..|..|.:.||::..|:|:||:.:| ..|.||||.|.||..
 Worm   552 NIYKRLE-HTVSFIKNRNAAVKNINRLSKADVVQLREREDVCAICFIEMKEEARITPCKHYFHGP 615

Zfish   560 CLKKWLYVQETCPLCHNQLK-----------------GSSQLGSSSQDVP--PQDTPAQPEEDQD 605
            ||:|||.|:..||||:..:|                 ..::.|::.::.|  |::.|..|..::.
 Worm   616 CLRKWLAVKMVCPLCYTYMKEDDFDSKSSSSGTLNEVQQNEEGAAVEENPENPEEQPEAPNAERA 680

Zfish   606 PSEPAD 611
            |.:..|
 Worm   681 PGDMFD 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf145a	XP_005157379.1	TRC8_N	8..506	CDD:290425	149/523 (28%)
		zf-RING_2	535..575	CDD:290367	22/40 (55%)
rnf-145	NP_491382.2	TRC8_N	49..556	CDD:372682	148/518 (29%)
		RING-H2_RNF139_like	590..631	CDD:319390	22/40 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	207	1.000	Domainoid score	I1833
eggNOG	1	0.900	-	-		E1_COG5243
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H137692
Inparanoid	1	1.050	279	1.000	Inparanoid score	I2008
OMA	1	1.010	-	-		QHG46488
OrthoDB	1	1.010	-	-		D302551at33208
OrthoFinder	1	1.000	-	-		FOG0006288
OrthoInspector	1	1.000	-	-		otm12138
orthoMCL	1	0.900	-	-		OOG6_109881
Panther	1	1.100	-	-	O	PTHR22763
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7680
SonicParanoid	1	1.000	-	-		X4575
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.870