Protein Alignment KLK6 and CG18735

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_652645.1
• Gene: CG18735 / 59137
• FlyBaseID: FBgn0042098
• Length: 364
• Species: Drosophila melanogaster
• Alignment Length: 234
• Identity: 85/234 - (36%)
• Similarity: 123/234 - (52%)
• Gaps: 17/234 - (7%)

Human    19 QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKK----PNLQVFLGKHNLRQ 79
            ::::|.|...:...:|:...|...|:..||..|::..:.||||||..    ..:.|.|.:||.:.
  Fly    80 RHRIVGGQETEVHEYPWMIMLMWFGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQD 144

Human    80 RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSANTTSCHILG 142
            .........|.|.:|||.|...:.|.||.|:|...|.:|...:.|  :|...:..|..|:. :.|
  Fly   145 SHVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLGIDMHPVCMPTPSENYAGQTAV-VTG 208

Human   143 WGKTAD-GDFPDTIQCAYIHLVSREECEHAYPGQ--ITQNMLCAG-DEKYGKDSCQGDSGGP--- 200
            ||..:: |...||:|...:.::|:|||.::..|:  ||.||:||| .|:.||||||||||||
  Fly   209 WGALSEGGPISDTLQEVEVPILSQEECRNSNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHV 273

Human   201 LVCGD--HLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
            |..||  .|.|:||||. .|.....|||||.|..:.:||
  Fly   274 LGSGDAYQLAGIVSWGE-GCAKPNAPGVYTRVGSFNDWI 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	83/228 (36%)
CG18735	NP_652645.1	Tryp_SPc	83..314	CDD:238113	85/231 (37%)