Protein Alignment KLK6 and CG34458

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001097340.1
• Gene: CG34458 / 5740868
• FlyBaseID: FBgn0085487
• Length: 257
• Species: Drosophila melanogaster
• Alignment Length: 250
• Identity: 78/250 - (31%)
• Similarity: 129/250 - (51%)
• Gaps: 18/250 - (7%)

Human     3 KLMVVLSLIAAAWAE----EQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63
            ||.::|..:....::    |:::::.|........|:|.:|..:|...|||.||....::|||||
  Fly     9 KLSILLLAVTFVHSDMDVAEESRIIGGQFAAPGQFPHQVSLQLNGRHHCGGSLISDTMIVTAAHC 73

Human    64 ---KKP-NLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP 124
               :.| .::..:|.::|  ...:.:..::.:.:|||.|:..|.|.|:.|::|:.|..:...:|.
  Fly    74 TMGQNPGQMKAIVGTNDL--SAGNGQTFNIAQFIIHPRYNPQSQDFDMSLIKLSSPVPMGGAVQT 136

Human   125 LPLERDCSAN---TTSCHILGWGKTADG-DFPDTIQCAYIHLVSREEC-EHAYPGQITQNMLCAG 184
            :.| .|..:|   .|...|.|:|..... ..|:.::.|.:.|.||:.| ....|| :|..|:|||
  Fly   137 IQL-ADSDSNYAADTMAMISGFGAINQNLQLPNRLKFAQVQLWSRDYCNSQNIPG-LTDRMVCAG 199

Human   185 DEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQK 239
            .......||||||||||.....|.|:|||| ..||:|.:|.:||.|....:||::
  Fly   200 HPSGQVSSCQGDSGGPLTVDGKLFGVVSWG-FGCGAKGRPAMYTYVGALRSWIKQ 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	72/222 (32%)
CG34458	NP_001097340.1	Tryp_SPc	32..254	CDD:238113	74/226 (33%)