Protein Alignment KLK6 and CG34436

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001097954.1
• Gene: CG34436 / 5740743
• FlyBaseID: FBgn0085465
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 230
• Identity: 62/230 - (26%)
• Similarity: 100/230 - (43%)
• Gaps: 32/230 - (13%)

Human    32 SHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC--KKPNLQVFLGKHNLRQR---ESSQEQSSVVR 91
            |.|:. ||....:..|.|.|||..:|:|:|.|  .:....|.||:.:::|.   ..|.:...|..
  Fly    40 SRPWM-ALVLLPNKTCSGALIHKYFVITSASCVFNQERAIVRLGQLSIKQEHIVSYSSDDYHVQS 103

Human    92 AVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSC----HILGWGKTADGDFP 152
            |.||..|:.::.:.||.||.|.........|:|:.|..|.|...|..    ....||.......|
  Fly   104 AYIHRFYEKSNFEHDIALLELQNDVLYKAHIRPICLWLDKSDIDTQMFKRYETFRWGIDEKYILP 168

Human   153 DTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLR--------- 208
             ..:.:.|..:|:.:||:|:......:.:|||.:  .|..|. ::|.||.  ..:|
  Fly   169 -AAKTSKIKHISQVKCENAFKLYPQNSHICAGYK--NKSKCV-ETGSPLF--KKIRYYTKIRYTL 227

Human   209 -GLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242
             |:.|:|      :.:..:||:|.:|.:||...||
  Fly   228 FGIQSYG------ESRTCLYTDVTKYIDWIMGVIQ 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	58/223 (26%)
CG34436	NP_001097954.1	Tryp_SPc	40..252	CDD:473915	59/224 (26%)