Protein Alignment KLK6 and epsilonTry

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_525112.1
• Gene: epsilonTry / 49080
• FlyBaseID: FBgn0010425
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 271
• Identity: 81/271 - (29%)
• Similarity: 122/271 - (45%)
• Gaps: 46/271 - (16%)

Human     1 MKKLMVVLSLIAAAWA---------EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLW 56
            |.|..|:||::|.|.|         :...::|.|......:||||.:|...|...|||.:.....
  Fly     1 MLKFAVLLSVLACALAGTIPDGLLPQLDGRIVGGYETSIDAHPYQVSLQRYGSHFCGGSIYSHDI 65

Human    57 VLTAAHC----KKPNLQVFLGK---------HNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIM 108
            |:|||||    :..:|::.:|.         |::|...:            |..|::.:...||.
  Fly    66 VITAAHCLQSIEAKDLKIRVGSTYWRSGGSVHSVRSFRN------------HEGYNSRTMVNDIA 118

Human   109 LLRLARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREEC--- 168
            ::|:.........|:.:.:.........:..:.|||.|..|  ..||.:....:.::....|
  Fly   119 IIRIESDLSFRSSIREIRIADSNPREGATAVVSGWGTTESGGSTIPDHLLAVDLEIIDVSRCRSD 183

Human   169 EHAYPGQITQNMLCAGDEKYG--KDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC 231
            |..|..:|...||||    |.  ||:||||||||||.||.|.|:|||| ..||....||||.:|.
  Fly   184 EFGYGKKIKDTMLCA----YAPHKDACQGDSGGPLVSGDRLVGVVSWG-YGCGDVRYPGVYADVA 243

Human   232 RYTNWIQKTIQ 242
            .:..||::|.:
  Fly   244 HFHEWIERTAE 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	70/233 (30%)
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	70/235 (30%)