Protein Alignment KLK6 and betaTry

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_524904.1
• Gene: betaTry / 47901
• FlyBaseID: FBgn0010357
• Length: 253
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 84/260 - (32%)
• Similarity: 123/260 - (47%)
• Gaps: 34/260 - (13%)

Human     1 MKKLMVVLSLIAAAWA---------EEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLW 56
            |.|.:::||.:|.|..         :...::|.|.....:|.|:|.:|..||...|||.:.....
  Fly     1 MLKFLILLSAVACALGGTIPEGLLPQLDGRIVGGTATTISSFPWQISLQRSGSHSCGGSIYSARV 65

Human    57 VLTAAHC----KKPNLQVFLGKHNLRQRESSQEQSSVVRAVI-----HPDYDAASHDQDIMLLRL 112
            ::|||||    ...:||:..|        ||...|..|.|.:     |..|:|.:...||.:|.|
  Fly    66 IVTAAHCLQSVSASSLQIRAG--------SSYWSSGGVVAKVSSFKNHEGYNANTMVNDIAVLHL 122

Human   113 ARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADG--DFPDTIQCAYIHLVSREEC---EHAY 172
            :.....|..|:.:.|.....||..:..:.|||..:.|  ..|..::...:::||:..|   .:.|
  Fly   123 SSSLSFSSTIKAIGLASSNPANGAAASVSGWGTESSGSSSIPSQLRYVNVNIVSQSRCSSSSYGY 187

Human   173 PGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
            ..||..:|:||...  ||||||||||||||.|..|.|:|||| ..|.:...||||.:|....:|:
  Fly   188 GNQIKSSMICAFAS--GKDSCQGDSGGPLVSGGVLVGVVSWG-YGCAAANYPGVYADVAALRSWV 249

Human   238  237
              Fly   250  249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	77/227 (34%)
betaTry	NP_524904.1	Tryp_SPc	30..249	CDD:214473	77/229 (34%)