Protein Alignment KLK6 and Jon99Ci

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_524555.1
• Gene: Jon99Ci / 43545
• FlyBaseID: FBgn0003358
• Length: 272
• Species: Drosophila melanogaster
• Alignment Length: 236
• Identity: 68/236 - (28%)
• Similarity: 106/236 - (44%)
• Gaps: 22/236 - (9%)

Human    19 QNKLVHGGPCDKTSHPY--QAALYTSGH-LLCGGVLIHPLWVLTAAHCK--KPNLQVFLGKHNLR 78
            :.::.:|....:...||  ..:|.::|: ..|||.:|...||||||||.  .....::.|..|..
  Fly    38 EGRITNGNLASEGQVPYIVGVSLNSNGNWWWCGGSIIGHTWVLTAAHCTAGADEASLYYGAVNYN 102

Human    79 QRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARP-AKLSELIQPLPL----ERDCSANTTSC 138
            :.......|| ...:.:|.|....||    |..:..| .....|:..:.|    :|..|......
  Fly   103 EPAFRHTVSS-ENFIRYPHYVGLDHD----LALIKTPHVDFYSLVNKIELPSLDDRYNSYENNWV 162

Human   139 HILGWGKTADG-DFPDTIQCAYIHLVSREECEHAYPGQIT--QNMLCAGDEKYGKDSCQGDSGGP 200
            ...|||...|| :..:.::...:.::|..||: ||.|..|  :|.:|. :...||.:||||||||
  Fly   163 QAAGWGAIYDGSNVVEDLRVVDLKVISVAECQ-AYYGTDTASENTICV-ETPDGKATCQGDSGGP 225

Human   201 LVC--GDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQK 239
            ||.  ||.|.|:.|:.:........|..:|.|.:|..||::
  Fly   226 LVTKEGDKLIGITSFVSAYGCQVGGPAGFTRVTKYLEWIKE 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	66/228 (29%)
Jon99Ci	NP_524555.1	Tryp_SPc	41..266	CDD:238113	68/231 (29%)