Protein Alignment KLK6 and Jon99Cii

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_524554.1
• Gene: Jon99Cii / 43544
• FlyBaseID: FBgn0003356
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 276
• Identity: 78/276 - (28%)
• Similarity: 118/276 - (42%)
• Gaps: 59/276 - (21%)

Human     3 KLMVVLSL-IAAAWA--------------EEQNKLVHGGPCDKTSHPYQAALYTS--GHLLCGGV 50
            ||.|.|:| :|||.|              :.|.::.:|.|..:...||...|..|  |:..|||.
  Fly     2 KLFVFLALAVAAATAVPAPAQKLTPTPIKDIQGRITNGYPAYEGKVPYIVGLLFSGNGNWWCGGS 66

Human    51 LIHPLWVLTAAHC----------------KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYD 99
            :|...||||||||                .:|....::|..::.|               |..|:
  Fly    67 IIGNTWVLTAAHCTNGASGVTINYGASIRTQPQYTHWVGSGDIIQ---------------HHHYN 116

Human   100 AASHDQDIMLLRLARPAKLSELIQ--PLPLERDCSANTTSCHIL--GWGKTADGD-FPDTIQCAY 159
            :.:...||.|:|... .....|:.  .||...|...:......:  |||.|.||. .||.:|...
  Fly   117 SGNLHNDISLIRTPH-VDFWSLVNKVELPSYNDRYQDYAGWWAVASGWGGTYDGSPLPDWLQSVD 180

Human   160 IHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVC--GDHLRGLVSWGNIPCGSKE 222
            :.::|:.:|...:  .:..||:|...:. ||.:|.||||||||.  |:.|.|:.|:|:.......
  Fly   181 VQIISQSDCSRTW--SLHDNMICINTDG-GKSTCGGDSGGPLVTHDGNRLVGVTSFGSAAGCQSG 242

Human   223 KPGVYTNVCRYTNWIQ 238
            .|.|::.|..|.:||:
  Fly   243 APAVFSRVTGYLDWIR 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	66/238 (28%)
Jon99Cii	NP_524554.1	Tryp_SPc	36..260	CDD:238113	68/242 (28%)