Protein Alignment KLK6 and CG11843

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_651663.1
• Gene: CG11843 / 43432
• FlyBaseID: FBgn0039630
• Length: 316
• Species: Drosophila melanogaster
• Alignment Length: 257
• Identity: 75/257 - (29%)
• Similarity: 106/257 - (41%)
• Gaps: 48/257 - (18%)

Human    22 LVHGGPCDKTSHPYQAAL------YTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNL--- 77
            :|.|.|......|:.|.|      .:.....||||||...:|||||||    |:...|:.|:
  Fly    68 IVGGHPAQPREFPHMARLGRRPDPSSRADWFCGGVLISERFVLTAAHC----LESERGEVNVVRL 128

Human    78 -------RQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQP--LPLERDCSA 133
                   ...:::.....|...:.||.|:......||.|::|...........|  ||.:.:.|:
  Fly   129 GELDFDSLDEDAAPRDYMVAGYIAHPGYEDPQFYHDIGLVKLTEAVVFDLYKHPACLPFQDERSS 193

Human   134 NTTSCHILGWGKTADGDFPDT------IQ------CAYIHLVSREECEHAYPGQITQNMLCAGDE 186
            :  |...:|||.|.....|..      :|      |..:.....||....:.|   .|.||.|.|
  Fly   194 D--SFIAVGWGSTGLALKPSAQLLKVKLQRYGNWVCKKLLTRQVEEFPRGFDG---NNQLCVGSE 253

Human   187 KYGKDSCQGDSGGPLV-------CGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241
             ..:|:|.|||||||:       |...:.|:.|.| :.|||...||:||.|..|..||.:|:
  Fly   254 -MAQDTCNGDSGGPLLMYHREYPCMYVVVGITSAG-LSCGSPGIPGIYTRVYPYLGWIARTL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	72/250 (29%)
CG11843	NP_651663.1	Tryp_SPc	68..312	CDD:238113	74/254 (29%)