Protein Alignment KLK6 and CG11842

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_651662.1
• Gene: CG11842 / 43431
• FlyBaseID: FBgn0039629
• Length: 319
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 70/263 - (26%)
• Similarity: 106/263 - (40%)
• Gaps: 62/263 - (23%)

Human    22 LVHGGPCDKTSHPYQAALYTSGH--------LLCGGVLIHPLWVLTAAHCK-KPNLQVFLGK--- 74
            ::.|||......|:.|.|   ||        ..|||.||....|||||||. .|...|.:.:
  Fly    73 IIGGGPAVPKEFPHAARL---GHKDENGEVEWFCGGTLISDRHVLTAAHCHYSPQGSVNIARLGD 134

Human    75 --HNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTS 137
              .:....::..|...|.....||::...:...||.::||:||...::...|..|..|.....||
  Fly   135 LEFDTNNDDADPEDFDVKDFTAHPEFSYPAIYNDISVVRLSRPVTFNDYKHPACLPFDDGRLGTS 199

Human   138 CHILGWGKTADGDFPDTIQCAYIHLVSREE---------------C-------EHAYPGQITQNM 180
            ...:|||:              :.:|.|.|               |       :....|......
  Fly   200 FIAIGWGQ--------------LEIVPRTENKKLQKVKLYNYGTRCRITADRNDELPEGYNATTQ 250

Human   181 LCAGDEKYGKDSCQGDSGGPLV-------CGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQ 238
            ||.|..:: ||:|.||||||::       |..|:.|:.|.| :.|.:.:.|.:||.|..|.:||:
  Fly   251 LCIGSNEH-KDTCNGDSGGPVLIYHMDYPCMYHVMGITSIG-VACDTPDLPAMYTRVHFYLDWIK 313

Human   239 KTI 241
            :.:
  Fly   314 QQL 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	68/256 (27%)
CG11842	NP_651662.1	Tryp_SPc	73..315	CDD:238113	70/260 (27%)