Protein Alignment KLK6 and SPE

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_651168.1
• Gene: SPE / 42791
• FlyBaseID: FBgn0039102
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 236
• Identity: 67/236 - (28%)
• Similarity: 106/236 - (44%)
• Gaps: 42/236 - (17%)

Human    47 CGGVLIHPLWVLTAAHCKKPN---------LQVFLGKHNLRQRESSQEQSS-------------V 89
            |||.|::..:||||.||....         ..|.||:.:.|.......|.:             |
  Fly   166 CGGALLNSRYVLTAGHCLASRELDKSGAVLHSVRLGEWDTRTDPDCTTQMNGQRICAPKHIDIEV 230

Human    90 VRAVIHPDYDAASHDQ--DIMLLRLARPAKLSELIQPLPLERDCSANTT----SCHILGWGKTAD 148
            .:.:||..|...|.||  ||.|:||.|....::.::|:.|..|......    ...:.|||.|.:
  Fly   231 EKGIIHEMYAPNSVDQRNDIALVRLKRIVSYTDYVRPICLPTDGLVQNNFVDYGMDVAGWGLTEN 295

Human   149 GDFPDTIQCAY-IHLVSREECEHAYPG---QITQNMLCAGDEKYGKDSCQGDSGGPLV----CGD 205
            .. |..|:... :::.:...|:..|..   ::..:.:|||.: .|.|:|.|||||||:    .|.
  Fly   296 MQ-PSAIKLKITVNVWNLTSCQEKYSSFKVKLDDSQMCAGGQ-LGVDTCGGDSGGPLMVPISTGG 358

Human   206 ----HLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242
                ::.|:.|:|..|||.|..|||||....:.:||::.::
  Fly   359 RDVFYIAGVTSYGTKPCGLKGWPGVYTRTGAFIDWIKQKLE 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	65/229 (28%)
SPE	NP_651168.1	CLIP	36..94	CDD:463440
		Tryp_SPc	135..397	CDD:238113	67/232 (29%)