Protein Alignment KLK6 and CG5255

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_650604.1
• Gene: CG5255 / 42073
• FlyBaseID: FBgn0038485
• Length: 273
• Species: Drosophila melanogaster
• Alignment Length: 255
• Identity: 74/255 - (29%)
• Similarity: 119/255 - (46%)
• Gaps: 22/255 - (8%)

Human     1 MKKLMVVLSLIAAAWAEE--------QNKLVHGGPCDKTSHPYQAAL--YTSGHLLCGGVLIHPL 55
            |..:::.|.|..::.|.:        :|::|.|........|||.:|  ..||...|||.:|...
  Fly     1 MLLILLPLVLFTSSAASQILYPPQYTKNRIVGGEEAAAGLAPYQISLQGIGSGAHSCGGAIIDER 65

Human    56 WVLTAAHCKKPN----LQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPA 116
            |::|||||.:..    .:|..|..:|.|..|......  |.|.|.:|....:..||.||.|....
  Fly    66 WIITAAHCTRGRQATAFRVLTGTQDLHQNGSKYYYPD--RIVEHSNYAPRKYRNDIALLHLNESI 128

Human   117 KLSELIQPLPLERDCSANTTSCHILGWGK-TADGDFPDTIQCAYIHLVSREECEHAYPG--QITQ 178
            ......||:.|:.:.....:...:.|||. :..||.|..:|...::.|..|:|..|:..  ::..
  Fly   129 VFDNATQPVELDHEALVPGSRLLLTGWGTLSLGGDVPARLQSLEVNYVPFEQCRAAHDNSTRVDI 193

Human   179 NMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQ 238
            ..:|..::| |:.:|.||||||||....|..||:|| :|| :|..|..:.::..|.::|:
  Fly   194 GHVCTFNDK-GRGACHGDSGGPLVHNGKLVALVNWG-LPC-AKGYPDAHASISYYHDFIR 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	68/222 (31%)
CG5255	NP_650604.1	Tryp_SPc	29..249	CDD:214473	68/224 (30%)