Protein Alignment KLK6 and CG4053

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_650601.2
• Gene: CG4053 / 42070
• FlyBaseID: FBgn0038482
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 232
• Identity: 64/232 - (27%)
• Similarity: 112/232 - (48%)
• Gaps: 19/232 - (8%)

Human    20 NKLVHGGPCDKTSHPYQAALYT--SGHLLCGGVLIHPLWVLTAAHC----KKPNLQVFLGKHNLR 78
            |::|.|...:....|||.::.|  ..| :|.||:::..|:|||.||    ...:|::.:|.::
  Fly    33 NRIVGGQEAEDGVAPYQVSIQTIWKTH-ICSGVILNEQWILTAGHCALDFSIEDLRIIVGTND-- 94

Human    79 QRESSQEQSSVVRAVIHPDYDAA-SHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHILG 142
             |....:......|::|..||.. .::.||.|:.:......::..|.:.|.|:.....::..:.|
  Fly    95 -RLEPGQTLFPDEALVHCLYDIPYVYNNDIALIHVNESIIFNDRTQIVELSREQPPAGSTVTLTG 158

Human   143 WGKTADGDFPDT--IQCAYIHLVSREECEHA--YPGQITQNMLCAGDEKYGKDSCQGDSGGPLVC 203
            || ..:..:|..  :|...:.:::.|||...  :...|....:|....: |:.:|.|||||||:.
  Fly   159 WG-APESSYPTVQYLQTLNLTIIAHEECRERWDFHDGIDIGHICTFTRE-GEGACSGDSGGPLMW 221

Human   204 GDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKT 240
            ...|.|||:||. .|| ...|.:|.|...|.:||::|
  Fly   222 EGKLVGLVNWGR-ACG-VGMPDMYANTVYYQDWIRRT 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	60/224 (27%)
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	62/228 (27%)