Protein Alignment KLK6 and CG17477

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_650598.1
• Gene: CG17477 / 42067
• FlyBaseID: FBgn0038479
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 263
• Identity: 78/263 - (29%)
• Similarity: 118/263 - (44%)
• Gaps: 46/263 - (17%)

Human     4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYT-SGHLLCGGVLIHPLWVLTAAHCKK-- 65
            ::|..||.....|.| :.:|.|....:...|||.:|.| .|..||||.:|...|::||.||.|
  Fly    10 ILVFSSLYCDLLALE-HFIVGGQNAAEGDAPYQVSLQTLLGSHLCGGAIISDRWIITAGHCVKGY 73

Human    66 --PNLQVFLGKHNLRQRESSQEQSSVVRAVIHPD-------YDAASHDQDIMLLRLARPAKLSEL 121
              ..|||..|  .:|..|..        ||.:||       ||:..:..||.||.|......:.|
  Fly    74 PTSRLQVATG--TIRYAEPG--------AVYYPDAIYLHCNYDSPKYQNDIGLLHLNESITFNAL 128

Human   122 IQPL-----PLERDCSANTTSCHILGWG-KTADGDFPDTIQCAYIHLVSREECE---HAYPG-QI 176
            .|.:     |..|..|    .....||| ::|.|..|..:|......::...||   .||.. ::
  Fly   129 TQAVELPTSPFPRGAS----ELVFTGWGSQSAAGSLPSQLQRVQQQHLNSPACESMMSAYEDLEL 189

Human   177 TQNMLCAGDEKYGK---DSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQ 238
            ....:||    |.:   .:|.||||||||....|.|:::: .:|| ::..|.::.|:..|.:|::
  Fly   190 GPCHICA----YRQANIGACHGDSGGPLVHQGTLVGILNF-FVPC-AQGVPDIFMNIMYYRDWMR 248

Human   239 KTI 241
            :|:
  Fly   249 QTM 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/238 (30%)
CG17477	NP_650598.1	Tryp_SPc	27..250	CDD:238113	72/242 (30%)