Protein Alignment KLK6 and CG10405

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001036717.1
• Gene: CG10405 / 41996
• FlyBaseID: FBgn0038431
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 76/259 - (29%)
• Similarity: 121/259 - (46%)
• Gaps: 35/259 - (13%)

Human     4 LMVVLSLI---AAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKK 65
            ::|:|...   ||...:..:::|:|....:...|||.:|......:||..::...|.:|||||
  Fly    16 ILVILEASRTEAAVPRQPDSRIVNGREATEGQFPYQLSLRRQTVHICGASILSSNWAITAAHC-- 78

Human    66 PNLQVFLGKHNLRQRESSQEQSSV----------VRAVI-HPDYDAASHDQDIMLLRLARPAKLS 119
                  :..|..:.||.:..|.|:          |:|:. ||.||.|..:.|:.|||.|..|...
  Fly    79 ------IDGHEQQPREFTLRQGSIMRTSGGTVQPVKAIYKHPAYDRADMNFDVALLRTADGALSL 137

Human   120 EL--IQP--LPLERDCSANTTSCHILGWG--KTADGDFPDTIQCAYIHLVSREECEH--AYPGQI 176
            .|  :.|  ||...:..:.:....:.|||  .|::......::...:..|::|:|.:  .:.|.:
  Fly   138 PLGKVAPIRLPTVGEAISESMPAVVSGWGHMSTSNPVLSSVLKSTTVLTVNQEKCHNDLRHHGGV 202

Human   177 TQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYT--NWIQ 238
            |:.|.||...  ..|:||||||||:.....|.|:|||| :.|.....|||||.:...|  .||:
  Fly   203 TEAMFCAAAR--NTDACQGDSGGPISAQGTLIGIVSWG-VGCADPYYPGVYTRLAHPTIRRWIR 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	70/234 (30%)
CG10405	NP_001036717.1	Tryp_SPc	36..262	CDD:214473	70/236 (30%)