Protein Alignment KLK6 and Sb

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_476709.1
• Gene: Sb / 41958
• FlyBaseID: FBgn0003319
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 74/252 - (29%)
• Similarity: 127/252 - (50%)
• Gaps: 27/252 - (10%)

Human    16 AEEQNKLVHGGPCDKTSHPYQAAL-------YTSGHLLCGGVLIHPLWVLTAAHCKK----PNLQ 69
            |..:.::|.|........|:|.::       ::|.| .|||.||:..|:.||.||..    ..::
  Fly   538 ARPETRIVGGKSAAFGRWPWQVSVRRTSFFGFSSTH-RCGGALINENWIATAGHCVDDLLISQIR 601

Human    70 VFLGKHNLR--QRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPL-ERDC 131
            :.:|:::..  |.:....:..|.:.|:||.|...:::.|:.|::|.:|.:.:..:.|:.| |.|.
  Fly   602 IRVGEYDFSHVQEQLPYIERGVAKKVVHPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPETDS 666

Human   132 SANTTSCHILGWGKTAD-GDFPDTIQCAYIHLVSREECEHAY--PGQ---ITQNMLCAGDEKYGK 190
            .....:..:.|||:.:: |..|..:|...:.:||.:.|:..:  .|:   |....||||.|..|:
  Fly   667 LLIGMNATVTGWGRLSEGGTLPSVLQEVSVPIVSNDNCKSMFMRAGRQEFIPDIFLCAGYETGGQ 731

Human   191 DSCQGDSGGPLVCGDH-----LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242
            |||||||||||.....     |.|::||| |.|.....|||.|.:.::|.||.:.::
  Fly   732 DSCQGDSGGPLQAKSQDGRFFLAGIISWG-IGCAEANLPGVCTRISKFTPWILEHVR 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/238 (30%)
Sb	NP_476709.1	Tryp_SPc	544..785	CDD:238113	73/242 (30%)