Protein Alignment KLK6 and CG3916

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_650167.1
• Gene: CG3916 / 41484
• FlyBaseID: FBgn0038003
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 275
• Identity: 79/275 - (28%)
• Similarity: 122/275 - (44%)
• Gaps: 52/275 - (18%)

Human     5 MVVLSL-------------IAAAWAEEQNKLVHGGPCDKTSHPYQAALYTS-----GHLLCGGVL 51
            ||||.|             :..:..|...: ::||.....:.|:|.:|...     .| .|||.:
  Fly     1 MVVLQLFCMLLILRQGLADVVTSTTESPTR-INGGQRVNETVPFQVSLQMQRRGRWQH-FCGGSI 63

Human    52 IHPLWVLTAAHC----KKPNLQVFLGKHN-----LRQRESSQEQSSVVRAVIHPDYDAASH-DQD 106
            :....|||||||    |..::.|.:|..|     ||.|        :|...:||.|..... ..|
  Fly    64 VSGQHVLTAAHCMEKMKVEDVSVVVGTLNWKAGGLRHR--------LVTKHVHPQYSMNPRIIND 120

Human   107 IMLLRLARPAKL--SELIQPLPLERDCSANTTSCHILGWG----KTADGDFPDTIQCAYIHLVSR 165
            |.|:::..|.:|  |::...|....|.........:.|||    .|:....||.:|......:|.
  Fly   121 IALVKVTPPFRLERSDISTILIGGSDRIGEKVPVRLTGWGSTSPSTSSATLPDQLQALNYRTISN 185

Human   166 EECEHAYPG-QITQNMLCAGDEKYGKDSCQGDSGGPLV---CGDHLRGLVSWGNIPCGSKEKPGV 226
            |:|..  .| ::|:|.:||...: |:.:|.|||||||:   ...||.|:||:|:..| ::.:|.|
  Fly   186 EDCNQ--KGFRVTRNEICALAVQ-GQGACVGDSGGPLIRPGKQPHLVGIVSYGSSTC-AQGRPDV 246

Human   227 YTNVCRYTNWIQKTI 241
            ||.|..:..:|.:.|
  Fly   247 YTRVSSFLPYISQVI 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/238 (30%)
CG3916	NP_650167.1	Tryp_SPc	30..257	CDD:214473	71/240 (30%)