Protein Alignment KLK6 and CG16749

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_649881.1
• Gene: CG16749 / 41111
• FlyBaseID: FBgn0037678
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 261
• Identity: 79/261 - (30%)
• Similarity: 121/261 - (46%)
• Gaps: 34/261 - (13%)

Human     5 MVVLSLIAAA----WAEEQNKLVHGGPCDKTSHPYQAALY-TSGHLLCGGVLIHPLWVLTAAHC- 63
            :.|.:|:..|    .|.:..::|:|.......:|:..::. :||...|||.:|...:|:|||||
  Fly     9 LAVFALLTTAGISHGAPQMGRVVNGTDSSVEKYPFVISMRGSSGSHSCGGSIISKQFVMTAAHCT 73

Human    64 ---KKPNLQVFLGKHNLRQRESSQEQSSVVRA---VIHPDYDA-ASHDQDIMLLRL--------- 112
               |..:|.|..|...:     :....:|||.   :.|.||:. .::..||.||.:
  Fly    74 DGRKASDLSVQYGVTKI-----NATGPNVVRVKKIIQHEDYNPYNNYANDISLLLVEEPFEFDGV 133

Human   113 -ARPAKLSELIQPLPLERDCSANTTSCHILGWGKTADGDF-PDTIQCAYIHLVSREECEHAYPGQ 175
             ..|.||.||....| :.|......   ::|||..|.|.: ..|:|...:.:.|.|||...:.|:
  Fly   134 TVAPVKLPELAFATP-QTDAGGEGV---LIGWGLNATGGYIQSTLQEVELKVYSDEECTERHGGR 194

Human   176 ITQNM-LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQK 239
            ..... :|.|.::.||..|.|||||||:......|:|||...||.....||||..|.:|.:||:|
  Fly   195 TDPRYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIKK 259

Human   240 T 240
            :
  Fly   260 S 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	72/234 (31%)
CG16749	NP_649881.1	Tryp_SPc	30..259	CDD:238113	74/237 (31%)