Protein Alignment KLK6 and CG12951

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_649880.1
• Gene: CG12951 / 41110
• FlyBaseID: FBgn0037677
• Length: 265
• Species: Drosophila melanogaster
• Alignment Length: 257
• Identity: 77/257 - (29%)
• Similarity: 119/257 - (46%)
• Gaps: 31/257 - (12%)

Human     4 LMVVLSLIAAAWAEEQ-NKLVHGGPCDKTSHPYQAAL--YTSGHLLCGGVLIHPLWVLTAAHCK- 64
            |:|:|::.....|... :::|:|.......:|:..:|  |...| .|||.:|...:|:|||||.
  Fly    11 LIVILAVTTVGQAAPSISRVVNGTDSSVLKYPFVVSLRSYDGSH-SCGGSIISKHFVMTAAHCTN 74

Human    65 -KP--NLQVFLGKHNLRQRESSQEQSSVV---RAVIHPDYDAASHD-QDIMLLRLARPAKLSEL- 121
             :|  .|.:..|..|:     |....:||   :.:.|.|:|....: .||.||.:..|.:...:
  Fly    75 GRPADTLSIQFGVTNI-----SAMGPNVVGIKKIIQHEDFDPTRQNANDISLLMVEEPFEFDGVS 134

Human   122 IQPLPL--------ERDCSANTTSCHILGWG-KTADGDFPDTIQCAYIHLVSREECEHAYPGQIT 177
            :.|:.|        :.|......   ::||| ....|...||:|...:.:.|.|||...:.||..
  Fly   135 VAPVELPALAFAVPQSDAGVEGV---LIGWGLNDTYGSVQDTLQEVSLKIYSDEECTSRHNGQTD 196

Human   178 QNM-LCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQ 238
            ... :|.|.::.||..|.|||||||:......|:|||...||.....||||..|.:|.:||:
  Fly   197 PKYHICGGVDEGGKGQCSGDSGGPLIYNGQQVGIVSWSIKPCTVAPYPGVYCKVSQYVDWIK 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/234 (30%)
CG12951	NP_649880.1	Tryp_SPc	30..260	CDD:238113	73/238 (31%)