Protein Alignment KLK6 and CG7542

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648995.3
• Gene: CG7542 / 39960
• FlyBaseID: FBgn0036738
• Length: 270
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 77/267 - (28%)
• Similarity: 126/267 - (47%)
• Gaps: 25/267 - (9%)

Human     1 MKKLMVVLSLIAAAWA-----EEQNKLVHGGPCDKTSHPYQAALYTS-GH--LLCGGVLIHPLWV 57
            |.||:|.:.|:.:..|     :.:..:.:|.|.:....||||.|..| |:  ..|||.||...|:
  Fly     1 MMKLLVCVLLVGSCTAVPLLTDVEPYITNGEPAEVGQFPYQAGLNVSFGNWSTWCGGTLISHYWI 65

Human    58 LTAAHCK--KPNLQVFLGKHNL-RQRESSQEQSSVVRA--VIHPDYDAASHDQDIMLLRLARPAK 117
            :|||||.  ..::.|:||..|: .:.|..||:..|.::  ::|.:|.|::...||.|:||.....
  Fly    66 ITAAHCMDGAESVTVYLGAINIGDESEEGQERIMVEKSGIIVHSNYMASTVVNDISLIRLPAFVG 130

Human   118 LSELIQPLPLERDCSANTTSCHIL-----GWGKTADGDFPDTIQCAYIH--LVSREECEHAYPGQ 175
            .::.|:...|.|..:....:...:     |||:.:|.....:....|:.  ::....|...:.|.
  Fly   131 FTDRIRAASLPRRLNGQFPTYESIRAFASGWGRESDASDSVSPVLRYVEMPIMPHSLCRMYWSGA 195

Human   176 ITQNMLCAGDEKYGKDSCQGDSGGPLVC----GDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNW 236
            :::.|:|..... ||.:|.||||||||.    ..:|.|..|:|.........|.|:|.:..|.:|
  Fly   196 VSEKMICMSTTS-GKSTCHGDSGGPLVYKQGNSSYLIGSTSFGTSMGCQVGFPAVFTRISSYLDW 259

Human   237 IQKTIQA 243
            |...|.|
  Fly   260 ILNHIIA 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	67/232 (29%)
CG7542	NP_648995.3	Tryp_SPc	27..263	CDD:238113	69/236 (29%)