Protein Alignment KLK6 and Jon74E

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_001189126.2
• Gene: Jon74E / 39959
• FlyBaseID: FBgn0023197
• Length: 271
• Species: Drosophila melanogaster
• Alignment Length: 234
• Identity: 73/234 - (31%)
• Similarity: 112/234 - (47%)
• Gaps: 22/234 - (9%)

Human    23 VHGGPCDKTSH-PYQAALY----TSGHLLCGGVLIHPLWVLTAAHC--KKPNLQVFLGKHNLRQR 80
            :.||...:.:. |||..|.    ...:..||..||...::||||||  |...:..:|| ..||..
  Fly    32 IAGGELARANQFPYQVGLSIEEPNDMYCWCGASLISDRYLLTAAHCVEKAVAITYYLG-GVLRLA 95

Human    81 ESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSANTTSCHI----L 141
            .....:|:.....:|||::..|.:.||.|:||...|.|.:.|:|:.|....|:..:..::    .
  Fly    96 PRQLIRSTNPEVHLHPDWNCQSLENDIALVRLPEDALLCDSIRPIRLPGLSSSRNSYDYVPAIAS 160

Human   142 GWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCG 204
            |||:..|..  ..|.::..|..:.|.|:||::| ..|....:|. |...||.:|.||||||||..
  Fly   161 GWGRMNDESTAISDNLRYVYRFVESNEDCEYSY-ANIKPTNICM-DTTGGKSTCTGDSGGPLVYS 223

Human   205 DHLR------GLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
            |.::      |:.|:|.....:|..|.|:|.:..|.:||
  Fly   224 DPVQNADILIGVTSYGKKSGCTKGYPSVFTRITAYLDWI 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	71/232 (31%)
Jon74E	NP_001189126.2	Tryp_SPc	31..262	CDD:214473	71/232 (31%)