Protein Alignment KLK6 and CG4914

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648711.1
• Gene: CG4914 / 39597
• FlyBaseID: FBgn0036436
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 246
• Identity: 84/246 - (34%)
• Similarity: 123/246 - (50%)
• Gaps: 35/246 - (14%)

Human    18 EQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKP----NLQVFLGKHNLR 78
            :::::|.|.....:.:|:.|.|.......|||.||:..:|||||||.|.    .::|..|:|:..
  Fly   124 DESRIVGGTTTGVSEYPWMARLSYFNRFYCGGTLINDRYVLTAAHCVKGFMWFMIKVTFGEHDRC 188

Human    79 QRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLER-----DCSANTTSC 138
            ..:...|...|:|| ....:..::.|.||.||||.....::..|:|:.|.|     |....|.:.
  Fly   189 NDKERPETRFVLRA-FSQKFSFSNFDNDIALLRLNDRVPITSFIRPICLPRVEQRQDLFVGTKAI 252

Human   139 HILGWGKTADGDFPD-TIQCAYIHLVSREEC--EHAYPGQ-ITQNMLCAGDEKY----GKDSCQG 195
             ..|||...:...|. .:|...:.::..:||  :..|..: ||:||:|:|   |    |:|||||
  Fly   253 -ATGWGTLKEDGKPSCLLQEVEVPVLDNDECVAQTNYTQKMITKNMMCSG---YPGVGGRDSCQG 313

Human   196 DSGGPLVCGDHLR---------GLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
            |||||||   .||         |:||||| .|.....|||||.|.:|.:||
  Fly   314 DSGGPLV---RLRPDDKRFEQIGIVSWGN-GCARPNYPGVYTRVTKYLDWI 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	82/239 (34%)
CG4914	NP_648711.1	Tryp_SPc	128..363	CDD:238113	84/242 (35%)