Protein Alignment KLK6 and CG4613

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648707.2
• Gene: CG4613 / 39586
• FlyBaseID: FBgn0036427
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 239
• Identity: 81/239 - (33%)
• Similarity: 113/239 - (47%)
• Gaps: 32/239 - (13%)

Human    20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKH--------- 75
            |::|.|.......:|:.|.:.....|.|||.||:..:|||||||          .|
  Fly   135 NRIVGGTQVRTNKYPWIAQIIRGTFLFCGGTLINDRYVLTAAHC----------VHGMDMRGVSV 189

Human    76 NLRQRESSQEQSSVVRAV----IHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAN-- 134
            .|.|.:.|.....|.|:|    .|..||..|...||.||||.:|..|.:.::|..|..:...|
  Fly   190 RLLQLDRSSTHLGVTRSVAFAHAHVGYDPVSLVHDIALLRLDQPIPLVDTMRPACLPSNWLQNFD 254

Human   135 TTSCHILGWGKTADGDFPDTI-QCAYIHLVSREECE-HAYPGQITQNMLCAGDEKY-GKDSCQGD 196
            .....:.|||.:.:|....:: |...:.:::..:|. .:|...|...|:|||..|. |:|:||||
  Fly   255 FQKAIVAGWGLSQEGGSTSSVLQEVVVPIITNAQCRATSYRSMIVDTMMCAGYVKTGGRDACQGD 319

Human   197 SGGPLVCGD---HLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWI 237
            |||||:..|   .|.|:||:| ..|...:.|||||.|.||..||
  Fly   320 SGGPLIVRDRIFRLAGVVSFG-YGCAKPDAPGVYTRVSRYLEWI 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	78/234 (33%)
CG4613	NP_648707.2	Tryp_SPc	136..362	CDD:214473	78/236 (33%)