Protein Alignment KLK6 and CG11529

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648558.1
• Gene: CG11529 / 39395
• FlyBaseID: FBgn0036264
• Length: 287
• Species: Drosophila melanogaster
• Alignment Length: 245
• Identity: 75/245 - (30%)
• Similarity: 112/245 - (45%)
• Gaps: 29/245 - (11%)

Human    14 AWAEEQNKLVHGGPCDKTSHPYQAALYTS----GHLLCGGVLIHPLWVLTAAHCKK--PNLQVFL 72
            ::|..|:|.   |..:|  .|||..|...    ..:||||.|:...|:|||.||..  .:..|:|
  Fly    27 SYAVGQSKY---GRIEK--FPYQVMLIGKQLWRKRILCGGTLLDKRWILTAGHCTMGVTHYDVYL 86

Human    73 GKHNLRQRESSQEQSSVVRA---VIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPL----ERD 130
            |..::...|.|  ...|:|:   ::|..::..:...||.|::|.:....:..|||..|    ..|
  Fly    87 GTKSVEDTEVS--GGLVLRSNKFIVHERFNPETAANDIALVKLPQDVAFTPRIQPASLPSRYRHD 149

Human   131 CSANTTSCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS--C 193
            ..|. .|....|||...:....|::|...:.::|..||...| ..:|..::||   |..||.  |
  Fly   150 QFAG-MSVVASGWGAMVEMTNSDSMQYTELKVISNAECAQEY-DVVTSGVICA---KGLKDETVC 209

Human   194 QGDSGGPLVCGDH--LRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241
            .||||||||..|.  :.|:.|:|.........||.:|.|..|.:||:..|
  Fly   210 TGDSGGPLVLKDTQIVVGITSFGPADGCETNIPGGFTRVTHYLDWIESKI 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	69/230 (30%)
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	70/229 (31%)