Protein Alignment KLK6 and CG18179

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648340.1
• Gene: CG18179 / 39124
• FlyBaseID: FBgn0036023
• Length: 268
• Species: Drosophila melanogaster
• Alignment Length: 272
• Identity: 80/272 - (29%)
• Similarity: 125/272 - (45%)
• Gaps: 45/272 - (16%)

Human     1 MKKLMVVLSLIAAAWAEE------------------QNKLVHGGPCDKTSHPYQAALY--TSGH- 44
            ||..::.||:..|..|..                  :.::|:|.|..:...||...|.  |.|.
  Fly     1 MKLFLLTLSVALAVVAASPGFNRTSLLPQVTISEGAEGRIVNGYPAPEGKAPYIVGLLIRTDGSN 65

Human    45 --LLCGGVLIHPLWVLTAAHCKKPN-LQVFLGKH---NLRQRESSQEQSSVVRAVIHPDYDAASH 103
              .:..|.:|...|:||||||...: :::..|.:   |...|:|.:..:    .:.||::.|..
  Fly    66 SAAVGAGTIIASDWILTAAHCLTTDYVEIHYGSNWGWNGAFRQSVRRDN----FISHPNWPAEG- 125

Human   104 DQDIMLLRLARPAKLSELIQPLPL-----ERDCSANTTSCHILGWGKTADGDFPDTIQCAYIHLV 163
            .:||.|:| ......::||..:.|     |.|...:|. |...|||...:|:..|.:||..:.::
  Fly   126 GRDIGLIR-TPSVGFTDLINKVALPSFSEESDRFVDTW-CVACGWGGMDNGNLADWLQCMDVQII 188

Human   164 SREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLR--GLVSWGNIPCGSKEKPGV 226
            |..|||.:| |.:....:|. ....||.||.||||||||..|:.|  |::::|::.|.|  .|..
  Fly   189 SNSECEQSY-GTVASTDMCT-RRTDGKSSCGGDSGGPLVTHDNARLVGVITFGSVDCHS--GPSG 249

Human   227 YTNVCRYTNWIQ 238
            ||.|..|..||:
  Fly   250 YTRVTDYLGWIR 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	72/229 (31%)
CG18179	NP_648340.1	Tryp_SPc	40..263	CDD:238113	74/233 (32%)