Protein Alignment KLK6 and CG16998

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648134.1
• Gene: CG16998 / 38847
• FlyBaseID: FBgn0035795
• Length: 258
• Species: Drosophila melanogaster
• Alignment Length: 260
• Identity: 73/260 - (28%)
• Similarity: 120/260 - (46%)
• Gaps: 31/260 - (11%)

Human     1 MKKLMVVLSLIA---AAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAH 62
            |..|.::|.||.   .:....|.::|.|........|:.|::...|:..|...||..||::||.|
  Fly     1 MNILALILLLICGHKTSALSPQERIVGGVEVPIHLTPWLASITVHGNYSCSSALITSLWLVTAGH 65

Human    63 CKKPNLQVFLGKHNLRQ----RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123
            |.:     :...:::|.    .:...::.:||..::|||::..:.:.||.||:|.:...|...||
  Fly    66 CVQ-----YPDSYSVRAGSTFTDGGGQRRNVVSVILHPDFNLRTLENDIALLKLDKSFTLGGNIQ 125

Human   124 ----PLPLERDCSANTTSCHIL--GWGK--TADGDFPDTIQCAYIHLVSREECEHAYP---GQIT 177
                |||     |.|.....:|  |||.  ..|.:....::...:.::::..|:..|.   ..||
  Fly   126 VVKLPLP-----SLNILPRTLLVAGWGNPDATDSESEPRLRGTVVKVINQRLCQRLYSHLHRPIT 185

Human   178 QNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQ 242
            .:|:||...  |:|.|.||||.|||......|:||:.: .|.....|||||.:..|..||...::
  Fly   186 DDMVCAAGA--GRDHCYGDSGAPLVHRGSSYGIVSFAH-GCADPHFPGVYTRLANYVTWIFNVLE 247

Human   243  242
              Fly   248  247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	65/228 (29%)
CG16998	NP_648134.1	Tryp_SPc	24..242	CDD:214473	65/230 (28%)