Protein Alignment KLK6 and CG10469

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648025.1
• Gene: CG10469 / 38696
• FlyBaseID: FBgn0035678
• Length: 267
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 82/267 - (30%)
• Similarity: 117/267 - (43%)
• Gaps: 45/267 - (16%)

Human     4 LMVVLSLIAAAWAEEQNKL-VHGGPCDKTSH-PYQAAL--YTSGHL----LCGGVLIHPLWVLTA 60
            |:|..||:   :.:|...| :..|...|... |||..|  |..|..    :|||.::...|::||
  Fly     7 LIVQFSLV---FGQETGSLRIMNGTAAKAKQLPYQVGLLCYFEGSKDEPNMCGGTILSNRWIITA 68

Human    61 AHC---KKPNL---QVFLGKHNLRQRESSQEQSSVVR---AVIHPDYDAASHDQDIMLLRLARPA 116
            |||   .|.||   .:.:||     .:|..::..||.   .::|..:|..:...||.|::|.:..
  Fly    69 AHCLQDPKSNLWKVLIHVGK-----VKSFDDKEIVVNRSYTIVHKKFDRKTVTNDIALIKLPKKL 128

Human   117 KLSELIQPLPLERDCSANTT----SCHILGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQ-- 175
            ..::.|||..|.   ||..|    ...|.|||.|........:|.....::|.:|||..:..|
  Fly   129 TFNKYIQPAKLP---SAKKTYTGRKAIISGWGLTTKQLPSQVLQYIRAPIISNKECERQWNKQLG 190

Human   176 -----ITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLR---GLVSWG-NIPCGSKEKPGVYTNVC 231
                 :..|.....|.|.|. .|:||||||:|..|..|   |:||.| :..|..| .|.|.|.|.
  Fly   191 GKSKKVVHNGFICIDSKKGL-PCRGDSGGPMVLDDGSRTLVGIVSHGFDGECKLK-LPDVSTRVS 253

Human   232 RYTNWIQ 238
            .|..||:
  Fly   254 SYLKWIK 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	74/244 (30%)
CG10469	NP_648025.1	Tryp_SPc	23..259	CDD:214473	74/245 (30%)