Protein Alignment KLK6 and CG10472

DIOPT Version :10

• Sequence 1: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_648017.1
• Gene: CG10472 / 38688
• FlyBaseID: FBgn0035670
• Length: 290
• Species: Drosophila melanogaster
• Alignment Length: 279
• Identity: 79/279 - (28%)
• Similarity: 126/279 - (45%)
• Gaps: 51/279 - (18%)

Human     4 LMVVLSLIAAAWAEEQN------------------KLVHGGPCDKTSHPYQAAL---YTSGHLLC 47
            |..:|...|..|...:|                  ::..|...:....|||..|   .|.|...|
  Fly    11 LATILGAQAVDWNSVKNLNIETPMPKVHGETLPSGRITGGQIAEPNQFPYQVGLLLYITGGAAWC 75

Human    48 GGVLIHPLWVLTAAHCK---KPNLQVFLGKHNLRQRESSQEQSSVV------RAVIHPDYDAASH 103
            ||.:|...|::|||||.   ...:.|:||.|:   |.:::|:...:      ..::|.|:.|.:.
  Fly    76 GGTIISDRWIITAAHCTDSLTTGVDVYLGAHD---RTNAKEEGQQIIFVETKNVIVHEDWIAETI 137

Human   104 DQDIMLLRLARPAKLSELIQP--LPLERDCSANTTSCHIL--GWGKTADG--DFPDTIQCAYIHL 162
            ..||.|::|..|.:.::.|||  ||::.|..:.....:.:  ||||.:|.  ...|.:|.|.:.:
  Fly   138 TNDISLIKLPVPIEFNKYIQPAKLPVKSDSYSTYGGENAIASGWGKISDSATGATDILQYATVPI 202

Human   163 VSREECEHAYPGQITQNMLC---AGDEKYGKDSCQGDSGGPLVCGD---HLRGLVSWGNIPCGSK 221
            ::...|...|.|.:..:.:|   .|    |..:|.||||||||..|   .|.|..|:| |..|.:
  Fly   203 MNNSGCSPWYFGLVAASNICIKTTG----GISTCNGDSGGPLVLDDGSNTLIGATSFG-IALGCE 262

Human   222 EK-PGVYTNVCRYTNWIQK 239
            .. |||:|.:..|.:||::
  Fly   263 VGWPGVFTRITYYLDWIEE 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	72/238 (30%)
CG10472	NP_648017.1	Tryp_SPc	46..279	CDD:214473	72/240 (30%)